Literature summary for 2.3.1.217 extracted from

Oyarce, P.; De Meester, B.; Fonseca, F.; de Vries, L.; Goeminne, G.; Pallidis, A.; De Rycke, R.; Tsuji, Y.; Li, Y.; Van den Bosch, S.; Sels, B.; Ralph, J.; Vanholme, R.; Boerjan, W.
Introducing curcumin biosynthesis in Arabidopsis enhances lignocellulosic biomass processing (2019), Nat. Plants, 5, 225-237 .

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Application

Application	Comment	Organism
biofuel production	incorporation of curcumin and phenylpentanoids into lignin has a positive effect on saccharification yield after alkaline pretreatment. To design a lignin that is easier to degrade under alkaline conditions, curcumin (diferuloylmethane) is produced in the model plant Arabidopsis thaliana via simultaneous expression of the turmeric genes diketide-CoA synthase (DCS) and curcumin synthase 2 (CURS2). The transgenic plants produce a plethora of curcumin- and phenylpentanoid-derived compounds with no negative impact on growth. Catalytic hydrogenolysis gives evidence that both curcumin and phenylpentanoids are incorporated into the lignifying cell wall, thereby significantly increasing saccharification efficiency after alkaline pretreatment of the transgenic lines by 14-24% as compared with the wild type	Curcuma longa

Organism

Organism	UniProt	Comment	Textmining
Curcuma longa	C6L7V8	-	-

Synonyms

Synonyms	Comment	Organism
curcumin synthase 2	-	Curcuma longa
CURS2	-	Curcuma longa

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Release 2023.1 (January 2023)