Literature summary for 2.3.1.217 extracted from

Zhang, L.; Gao, B.; Wang, X.; Zhang, Z.; Liu, X.; Wang, J.; Mo, T.; Liu, Y.; Shi, S.; Tu, P.
Identification of a new curcumin synthase from ginger and construction of a curcuminoid-producing unnatural fusion protein diketide-CoA synthase - curcumin synthase (2016), RSC Adv., 6, 12519-12524.

No PubMed abstract available

Search for more literature for 2.3.1.217

Application

Application	Comment	Organism
synthesis	construction of a fusion protein diketide-CoA synthase::curcumin synthase. Comparing to CURS, the fusion protein shows similar substrate specificities and catalytic potentials to catalyze the formation of various curcuminoids, with increased yields of curcuminoids	Zingiber officinale

Cloned(Commentary)

Cloned (Comment)	Organism
-	Zingiber officinale

Organism

Organism	UniProt	Comment	Textmining
Zingiber officinale	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(4-coumaroyl)acetyl-CoA + 3-(4-hydroxyphenyl)propionyl-CoA + H2O	-	Zingiber officinale	2 CoA + tetrahydrobisdemethoxycurcumin + CO2	-	?
feruloyl-CoA + feruloylacetyl-CoA + H2O	-	Zingiber officinale	2 CoA + curcumin + CO2	-	?

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Release 2023.1 (January 2023)