Literature summary for 2.3.1.21 extracted from

Sorokina, N.; ODonnell, J.M.; McKinney, R.D.; Pound, K.M.; Woldegiorgis, G.; LaNoue, K.F.; Ballal, K.; Taegtmeyer, H.; Buttrick, P.M.; Lewandowski, E.D.
Recruitment of compensatory pathways to sustain oxidative flux with reduced carnitine palmitoyltransferase I activity characterizes inefficiency in energy metabolism in hypertrophied hearts (2007), Circulation, 115, 2033-2041.

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Application

Application	Comment	Organism
medicine	hypertrophied myocardium displays a significant shift in the relative isoform distribution of CPT1 isoforms, L-CPT1 expression dramatically increases relative to M-CPT1 expression	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Rattus norvegicus	5739	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
75000	-	determined by SDS-PAGE and Western Blot analysis	Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
palmitoyl-CoA + L-carnitine	Rattus norvegicus	-	CoA + L-palmitoylcarnitine	-	?

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	male Sprague-Dawley rat	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
heart	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
palmitoyl-CoA + L-carnitine	-	Rattus norvegicus	CoA + L-palmitoylcarnitine	-	?

Synonyms

Synonyms	Comment	Organism
carnitine palmitoyltransferase I	-	Rattus norvegicus

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Release 2023.1 (January 2023)