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Literature summary for 2.3.1.21 extracted from
- Isolation and purification of mitochondrial carnitine octanoyltransferase activities from beef heart (1981), J. Biol. Chem., 256, 9861-9868.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Bos taurus | 5739 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| additional information | - |
enzyme migrates as part of a detergent micelle with MW of 510000 on gel filtration | Bos taurus |
| 67000 | - |
x * 67000, SDS-PAGE | Bos taurus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acyl-CoA + L-carnitine | Bos taurus | - |
CoA + L-acylcarnitine | - |
r |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| heart | - |
Bos taurus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 47.5 | - |
purified enzyme | Bos taurus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acyl-CoA + L-carnitine | - |
Bos taurus | CoA + L-acylcarnitine | - |
r | |
| decanoyl-CoA + L-carnitine | best substrate | Bos taurus | CoA + L-decanoylcarnitine | - |
r | |
| hexanoyl-CoA + L-carnitine | - |
Bos taurus | CoA + L-hexanoylcarnitine | - |
r | |
| lauroyl-CoA + L-carnitine | best substrate | Bos taurus | CoA + L-lauroylcarnitine | - |
r | |
| myristoyl-CoA + L-carnitine | - |
Bos taurus | CoA + L-myristoylcarnitine | - |
? | |
| octanoyl-CoA + L-carnitine | - |
Bos taurus | CoA + L-octanoylcarnitine | - |
r | |
| palmitoyl-CoA + L-carnitine | - |
Bos taurus | CoA + L-palmitoylcarnitine | - |
r | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 67000, SDS-PAGE | Bos taurus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
assay at | Bos taurus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| additional information | - |
pI: 8.5 | Bos taurus |
| 8 | - |
assay at | Bos taurus |
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Release 2023.1 (January 2023)
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