Literature summary for 2.3.1.20 extracted from

Luo, X.A.; Zhu, Y.M.; Liu, T.T.; Wang, X.P.; Zhou, P.P.; Bao, Z.D.; Yu, L.J.
Identification and characterization of a novel diacylglycerol acyltransferase gene from Mortierella alpina (2017), Biotechnol. Lett., 39, 883-888 .

Search for more literature for 2.3.1.20

Cloned(Commentary)

Cloned (Comment)	Organism
gene MaDGAT, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic tree, recombinant expression in Saccharomyces cerevisiae strain H1246	Mortierella alpina

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
endoplasmic reticulum membrane	gene MaDGAT encodes one transmembrane region in its 5'-end. MaDGAT without the transmembrane region is still functional. Perhaps the N-terminal transmembrane region in MaDGAT functions only to anchor the enzyme to the endoplasmic reticulum	Mortierella alpina	5789	-
additional information	MaDGAT without the transmembrane region is a cytoplasmic protein	Mortierella alpina	-	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
acyl-CoA + 1,2-diacyl-sn-glycerol	Mortierella alpina	-	CoA + 1,2,3-triacylglycerol	-	?
acyl-CoA + 1,2-diacyl-sn-glycerol	Mortierella alpina M30	-	CoA + 1,2,3-triacylglycerol	-	?

Organism

Organism	UniProt	Comment	Textmining
Mortierella alpina	A0A1S6XXG5	-	-
Mortierella alpina M30	A0A1S6XXG5	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
acyl-CoA + 1,2-diacyl-sn-glycerol	-	Mortierella alpina	CoA + 1,2,3-triacylglycerol	-	?
acyl-CoA + 1,2-diacyl-sn-glycerol	-	Mortierella alpina M30	CoA + 1,2,3-triacylglycerol	-	?

Subunits

Subunits	Comment	Organism
?	x * 31300, about, sequence calculation	Mortierella alpina

Synonyms

Synonyms	Comment	Organism
DGAT	-	Mortierella alpina
diacylglycerol acyltransferase	-	Mortierella alpina
MaDGAT	-	Mortierella alpina

General Information

General Information	Comment	Organism
metabolism	diacylglycerol acyltransferase (DGAT) catalyzes the last and final committed step of the TAG biosynthesis pathway and this is the rate-limiting step for lipid accumulation in plants	Mortierella alpina

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Release 2023.1 (January 2023)