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Literature summary for 2.3.1.189 extracted from

  • Newton, G.L.; Buchmeier, N.; Fahey, R.C.
    Biosynthesis and functions of mycothiol, the unique protective thiol of actinobacteria (2008), Microbiol. Mol. Biol. Rev., 72, 471-494.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
desacetylmycothiol + acetyl-CoA Mycolicibacterium smegmatis last step in biosynthesis of mycothiol, the major thiol in most actinomycetes mycothiol + coenzyme A
-
?
desacetylmycothiol + acetyl-CoA Corynebacterium glutamicum last step in biosynthesis of mycothiol, the major thiol in most actinomycetes mycothiol + coenzyme A
-
?
desacetylmycothiol + acetyl-CoA Streptomyces coelicolor last step in biosynthesis of mycothiol, the major thiol in most actinomycetes mycothiol + coenzyme A
-
?
desacetylmycothiol + acetyl-CoA Rhodococcus jostii last step in biosynthesis of mycothiol, the major thiol in most actinomycetes mycothiol + coenzyme A
-
?
desacetylmycothiol + acetyl-CoA Mycobacterium tuberculosis last step in biosynthesis of mycothiol, the major thiol in most actinomycetes mycothiol + coenzyme A
-
?
desacetylmycothiol + acetyl-CoA Rhodococcus jostii RHA-1 last step in biosynthesis of mycothiol, the major thiol in most actinomycetes mycothiol + coenzyme A
-
?
desacetylmycothiol + acetyl-CoA Mycobacterium tuberculosis H37Rv last step in biosynthesis of mycothiol, the major thiol in most actinomycetes mycothiol + coenzyme A
-
?

Organism

Organism UniProt Comment Textmining
Corynebacterium glutamicum
-
-
-
Mycobacterium tuberculosis P9WJM7
-
-
Mycobacterium tuberculosis H37Rv P9WJM7
-
-
Mycolicibacterium smegmatis
-
-
-
Rhodococcus jostii
-
RHA-1
-
Rhodococcus jostii RHA-1
-
RHA-1
-
Streptomyces coelicolor
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
desacetylmycothiol + acetyl-CoA
-
Mycolicibacterium smegmatis mycothiol + coenzyme A
-
?
desacetylmycothiol + acetyl-CoA
-
Corynebacterium glutamicum mycothiol + coenzyme A
-
?
desacetylmycothiol + acetyl-CoA
-
Streptomyces coelicolor mycothiol + coenzyme A
-
?
desacetylmycothiol + acetyl-CoA
-
Rhodococcus jostii mycothiol + coenzyme A
-
?
desacetylmycothiol + acetyl-CoA
-
Mycobacterium tuberculosis mycothiol + coenzyme A
-
?
desacetylmycothiol + acetyl-CoA last step in biosynthesis of mycothiol, the major thiol in most actinomycetes Mycolicibacterium smegmatis mycothiol + coenzyme A
-
?
desacetylmycothiol + acetyl-CoA last step in biosynthesis of mycothiol, the major thiol in most actinomycetes Corynebacterium glutamicum mycothiol + coenzyme A
-
?
desacetylmycothiol + acetyl-CoA last step in biosynthesis of mycothiol, the major thiol in most actinomycetes Streptomyces coelicolor mycothiol + coenzyme A
-
?
desacetylmycothiol + acetyl-CoA last step in biosynthesis of mycothiol, the major thiol in most actinomycetes Rhodococcus jostii mycothiol + coenzyme A
-
?
desacetylmycothiol + acetyl-CoA last step in biosynthesis of mycothiol, the major thiol in most actinomycetes Mycobacterium tuberculosis mycothiol + coenzyme A
-
?
desacetylmycothiol + acetyl-CoA
-
Rhodococcus jostii RHA-1 mycothiol + coenzyme A
-
?
desacetylmycothiol + acetyl-CoA last step in biosynthesis of mycothiol, the major thiol in most actinomycetes Rhodococcus jostii RHA-1 mycothiol + coenzyme A
-
?
desacetylmycothiol + acetyl-CoA
-
Mycobacterium tuberculosis H37Rv mycothiol + coenzyme A
-
?
desacetylmycothiol + acetyl-CoA last step in biosynthesis of mycothiol, the major thiol in most actinomycetes Mycobacterium tuberculosis H37Rv mycothiol + coenzyme A
-
?

Synonyms

Synonyms Comment Organism
MSH acetyltransferase
-
Mycolicibacterium smegmatis
MSH acetyltransferase
-
Corynebacterium glutamicum
MSH acetyltransferase
-
Streptomyces coelicolor
MSH acetyltransferase
-
Rhodococcus jostii
MSH acetyltransferase
-
Mycobacterium tuberculosis
MSH synthase
-
Mycolicibacterium smegmatis
MSH synthase
-
Corynebacterium glutamicum
MSH synthase
-
Streptomyces coelicolor
MSH synthase
-
Rhodococcus jostii
MSH synthase
-
Mycobacterium tuberculosis
MshD
-
Streptomyces coelicolor
MshD
-
Mycolicibacterium smegmatis
MshD
-
Rhodococcus jostii
MshD
-
Mycobacterium tuberculosis
nshD
-
Corynebacterium glutamicum