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Literature summary for 2.3.1.184 extracted from
- The Aeromonas hydrophila LuxR homologue AhyR regulates the N-acyl homoserine lactone synthase, AhyI positively and negatively in a growth phase-dependent manner (2004), FEMS Microbiol. Lett., 241, 109-117.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| AhyR | the LuxR homologue AhyR regulates AhyI positively and negatively in a growth phase-dependent manner | Aeromonas hydrophila | |
| additional information | N-butyryl-L-homoserine-1,4-lactone induces the expression of AhyI, not by binding to DNA, requiring AhyR | Aeromonas hydrophila |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| recombinant maltose binding protein-fusion protein AhyR binds to the ahyI promoter region | Aeromonas hydrophila |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| AhyR | the AhyR regulates AhyI positively and negatively in a growth phase-dependent manner | Aeromonas hydrophila |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Aeromonas hydrophila | the LuxR homologue AhyR regulates AhyI positively and negatively in a growth phase-dependent manner, regulation overview | ? | - |
? |  |
| S-adenosyl-L-methionine + butyryl-[acyl-carrier protein] | Aeromonas hydrophila | substrate of AhyI | 5'-methylthioadenosine + N-butyryl-L-homoserine-1,4-lactone + [acyl-carrier protein] | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Aeromonas hydrophila | - |
pathogen of fish, humans, and amphibians, strain AH-1N, gene ahyI | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the LuxR homologue AhyR regulates AhyI positively and negatively in a growth phase-dependent manner, regulation overview | Aeromonas hydrophila | ? | - |
? | |
| S-adenosyl-L-methionine + butyryl-[acyl-carrier protein] | substrate of AhyI | Aeromonas hydrophila | 5'-methylthioadenosine + N-butyryl-L-homoserine-1,4-lactone + [acyl-carrier protein] | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AhyI | - |
Aeromonas hydrophila |
| N-acyl homoserine lactone synthase | - |
Aeromonas hydrophila |
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