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Literature summary for 2.3.1.183 extracted from

  • Droege-Laser, W.; Siemeling, U.; Puhler, A.; Broer, I.
    The metabolites of the herbicide L-phosphinothricin (glufosinate). Identification, stability, and mobility in transgenic, herbicide-resistant, and untransformed plants (1994), Plant Physiol., 105, 159-166.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.183

Cloned(Commentary)

Cloned (Comment) Organism
gene pat, expression in transgenic Nicotiana tabacum, Daucus carota, and Medicago sativa plants, the functional expression of gene pat confers resistance to the herbicide L-phosphinothricin Streptomyces viridochromogenes

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetyl-CoA + L-phosphinothricin Streptomyces viridochromogenes the enzyme confers resistance to the herbicide phosphinothricin, which is deaminated to form its corresponding oxo acid 4-methylphosphinico-2-oxo-butanoic acid, which subsequently is decarboxylated to form 3-methylphosphinico-propanoic acid, a stable compound in the plant CoA + L-N-acetylphosphinothricin
-
 ?
acetyl-CoA + L-phosphinothricin Streptomyces viridochromogenes DSM 40736 / JCM 4977 / BCRC 1201 / Tue 494 / Tu 494 the enzyme confers resistance to the herbicide phosphinothricin, which is deaminated to form its corresponding oxo acid 4-methylphosphinico-2-oxo-butanoic acid, which subsequently is decarboxylated to form 3-methylphosphinico-propanoic acid, a stable compound in the plant CoA + L-N-acetylphosphinothricin
-
 ?

Organism

Organism UniProt Comment Textmining
Streptomyces viridochromogenes
-
 strain Tü494
-
Streptomyces viridochromogenes DSM 40736 / JCM 4977 / BCRC 1201 / Tue 494 / Tu 494
-
 strain Tü494
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + L-phosphinothricin
-
 Streptomyces viridochromogenes CoA + L-N-acetylphosphinothricin
-
 ?
acetyl-CoA + L-phosphinothricin the enzyme confers resistance to the herbicide phosphinothricin, which is deaminated to form its corresponding oxo acid 4-methylphosphinico-2-oxo-butanoic acid, which subsequently is decarboxylated to form 3-methylphosphinico-propanoic acid, a stable compound in the plant Streptomyces viridochromogenes CoA + L-N-acetylphosphinothricin
-
 ?
acetyl-CoA + L-phosphinothricin
-
 Streptomyces viridochromogenes DSM 40736 / JCM 4977 / BCRC 1201 / Tue 494 / Tu 494 CoA + L-N-acetylphosphinothricin
-
 ?
acetyl-CoA + L-phosphinothricin the enzyme confers resistance to the herbicide phosphinothricin, which is deaminated to form its corresponding oxo acid 4-methylphosphinico-2-oxo-butanoic acid, which subsequently is decarboxylated to form 3-methylphosphinico-propanoic acid, a stable compound in the plant Streptomyces viridochromogenes DSM 40736 / JCM 4977 / BCRC 1201 / Tue 494 / Tu 494 CoA + L-N-acetylphosphinothricin
-
 ?

Cofactor

Cofactor Comment Organism Structure
acetyl-CoA
-
 Streptomyces viridochromogenes