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Literature summary for 2.3.1.177 extracted from

  • Beerhues, L.; Liu, B.
    Biosynthesis of biphenyls and benzophenones-evolution of benzoic acid-specific type III polyketide synthases in plants (2009), Phytochemistry, 70, 1719-1727.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Sorbus aucuparia
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-hydroxybenzoyl-CoA + malonyl-CoA
-
Sorbus aucuparia 4-hydroxycoumarin + CoA + CO2
-
?
malonyl-CoA + benzoyl-CoA
-
Sorbus aucuparia CoA + 3,5-dihydroxybiphenyl + CO2
-
?

Synonyms

Synonyms Comment Organism
biphenyl synthase
-
Sorbus aucuparia
BIS
-
Sorbus aucuparia

Expression

Organism Comment Expression
Sorbus aucuparia BIS is only expressed when plant is infected with microorganisms up

General Information

General Information Comment Organism
metabolism BIS is the key enzyme of biphenyl metabolism, producing for instance 3,5-dihydroxybiphenyl which is the precursor of the phytoalexins of the Maloideae. Sorbus aucuparia