Literature summary for 2.3.1.176 extracted from

Ma, H.; Ma, Y.; Liu, X.; Dyer, D.; Xu, P.; Liu, K.; Lan, Q.; Hong, H.; Peng, J.; Peng, R.
NMR structure and function of Helicoverpa armigera sterol carrier protein-2, an important insecticidal target from the cotton bollworm (2015), Sci. Rep., 5, 18186.

Search for more literature for 2.3.1.176

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Helicoverpa armigera

Crystallization (Commentary)

Crystallization (Comment)	Organism
NMR spectroscopy and docking simulations reveal that the folds of alpha-helices and beta-sheets interact together to form a hydrophobic cavity with putative entrance and exit openings, which serves as a tunnel for accommodation and transport of lipids	Helicoverpa armigera

Protein Variants

Protein Variants	Comment	Organism
F110W	reduced ability to bind with cholesterol	Helicoverpa armigera
F53A	reduced ability to bind with cholesterol	Helicoverpa armigera
F53W	strongly reduced ability to bind with cholesterol	Helicoverpa armigera
F89A	reduced ability to bind with cholesterol	Helicoverpa armigera
I117M	reduced ability to bind with cholesterol	Helicoverpa armigera
Q131A	reduced ability to bind with cholesterol	Helicoverpa armigera
Y51A	reduced ability to bind with cholesterol	Helicoverpa armigera
Y51W	reduced ability to bind with cholesterol	Helicoverpa armigera

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
16000	-	x * 16293, calculated, x * 16000, SDS-PAGE	Helicoverpa armigera
16293	-	x * 16293, calculated, x * 16000, SDS-PAGE	Helicoverpa armigera

Organism

Organism	UniProt	Comment	Textmining
Helicoverpa armigera	K7NSY9	-	-

Subunits

Subunits	Comment	Organism
?	x * 16293, calculated, x * 16000, SDS-PAGE	Helicoverpa armigera

General Information

General Information	Comment	Organism
physiological function	inhibitor-treated larvae at young stage show a significant decrease of cholesterol uptake in vivo	Helicoverpa armigera

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)