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Literature summary for 2.3.1.176 extracted from

  • McIntosh, A.L.; Atshaves, B.P.; Gallegos, A.M.; Storey, S.M.; Reibenspies, J.H.; Kier, A.B.; Meyer, E.; Schroeder, F.
    Structure of dehydroergosterol monohydrate and interaction with sterol carrier protein-2 (2008), Lipids, 43, 1165-1184.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
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Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P22307
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information SCP-2, significantly enhances disruption of the dihydroergosterol microcrystalline structure when in the presence of excess cholesterol. In experiments with model membranes containing 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, cholesterol, and 1,2-dioleoylsn-glycero-3-[phospho-L-serine], SCP-2 enhances exchange of sterol between microcrystals and large unilamellar vesicles nearly 92fold more in the initial rate than the spontaneous exchange Homo sapiens ?
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