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Literature summary for 2.3.1.165 extracted from
- Tolerance and specificity of recombinant 6-methylsalicylic acid synthase (1999), Metab. Eng., 1, 180-187.
Application
| Application | Comment | Organism |
|---|---|---|
| biotechnology | production of unnatural polyketides e.g. 4-hydroxy-6-methyl-2-pyrone in E. coli and yeast after heterologous expression of the enzyme | Penicillium griseofulvum |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli and Saccharomyces cerevisiae can be used for 4-hydroxy-6-methyl-2-pyrone production | Penicillium griseofulvum |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Penicillium griseofulvum | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetyl-CoA + malonyl-CoA + NADPH | - |
Penicillium griseofulvum | 6-methylsalicylate + CoA + CO2 + NADP+ | - |
? |  |
| acetyl-CoA + N-acetylcysteamine + NADPH | - |
Penicillium griseofulvum | ? | - |
? | |
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Release 2023.1 (January 2023)
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