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Literature summary for 2.3.1.16 extracted from

  • Miltiadou, D.; Hager-Theodorides, A.L.; Symeou, S.; Constantinou, C.; Psifidi, A.; Banos, G.; Tzamaloukas, O.
    Variants in the 3 untranslated region of the ovine acetyl-coenzyme A acyltransferase 2 gene are associated with dairy traits and exhibit differential allelic expression (2017), J. Dairy Sci., 100, 6285-6297 .
    View publication on PubMed

Application

Application Comment Organism
agriculture a single nucleotide substitution, a T to C transition located in the 3' untranslated region of the ACAA2 gene is significantly associated with total lactation production and milk protein percentage, with respective additive effects of 6.81 kg and -0.05%. A significant dominance effect of 0.46 kg is detected for milk fat yield. Homozygous TT and heterozygous CT animals exhibit higher milk yield compared with homozygous CC animals. mRNA expression of the ACAA2 gene from TT animals is 2.8- and 11.8fold higher in liver and mammary gland, respectively. The T allele is expressed at an average of 18% more compared with the C allele in the udder of randomly selected ewes Ovis aries

Organism

Organism UniProt Comment Textmining
Ovis aries G3CH53
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Synonyms

Synonyms Comment Organism
ACAA2
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Ovis aries