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Literature summary for 2.3.1.16 extracted from

  • Miyazawa, S.; Furuta, S.; Osumi, T.; Hashimoto, T.; Ui, N.
    Properties of peroxisomal 3-ketoacyl-CoA thiolase from rat liver (1981), J. Biochem., 90, 511-519.
    View publication on PubMed
Search for more literature for 2.3.1.16

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information overview: Km of peroxisomal and mitochondrial enzyme with various substrates Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Rattus norvegicus 5739
-
peroxisome
-
 Rattus norvegicus 5777
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40000
-
 2 * 40000, peroxisomal enzyme, SDS-PAGE Rattus norvegicus
41000
-
 2 * 41000, mitochondrial enzyme, SDS-PAGE Rattus norvegicus
41000
-
 mitochondrial enzyme, 4 * 41000 Rattus norvegicus
89000
-
 peroxisomal enzyme, sedimentation equilibrium Rattus norvegicus
154000
-
 mitochondrial enzyme, sedimentation equilibrium Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Reaction

Reaction Comment Organism Reaction ID
acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA ping-pong mechanism Rattus norvegicus
a

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CoA + 3-oxoacyl-CoA
-
 Rattus norvegicus acyl-CoA + acetyl-CoA
-
 ?
CoA + 3-oxodecanoyl-CoA
-
 Rattus norvegicus acetyl-CoA + octanoyl-CoA
-
 ?
CoA + 3-oxododecanoyl-CoA
-
 Rattus norvegicus acetyl-CoA + decanoyl-CoA
-
 ?
CoA + 3-oxohexadecanoyl-CoA
-
 Rattus norvegicus acetyl-CoA + tetradecanoyl-CoA
-
 ?
CoA + 3-oxohexanoyl-CoA
-
 Rattus norvegicus acetyl-CoA + butanoyl-CoA
-
 ?
CoA + 3-oxooctanoyl-CoA
-
 Rattus norvegicus acetyl-CoA + hexanoyl-CoA
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 40000, peroxisomal enzyme, SDS-PAGE Rattus norvegicus
dimer 2 * 41000, mitochondrial enzyme, SDS-PAGE Rattus norvegicus
tetramer mitochondrial enzyme, 4 * 41000 Rattus norvegicus

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
additional information
-
 enzyme exhibits reversible cold-lability: loss of acitvity at 4°C in the presence of NaCl, half-maximal inactivation in ice in 4 min Rattus norvegicus