Any feedback?
Literature summary for 2.3.1.16 extracted from
- Peroxisomal acetoacetyl-CoA thiolase and 3-ketoacyl-CoA thiolase from an n-alkane-utilizing yeast, Candida tropicalis: purification and characterization (1989), J. Biochem., 106, 474-478.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0088 | - |
3-oxooctanoyl-CoA | - |
Candida tropicalis |  |
| 0.0093 | - |
3-oxododecanoyl-CoA | - |
Candida tropicalis | |
| 0.01 | - |
acetoacetyl-CoA | 3-oxodecanoyl-CoA | Candida tropicalis | |
| 0.028 | - |
3-oxohexanoyl-CoA | - |
Candida tropicalis | |
| 0.059 | - |
3-oxopentanoyl-CoA | - |
Candida tropicalis | |
| 0.093 | - |
acetoacetyl-CoA | - |
Candida tropicalis | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| peroxisome | - |
Candida tropicalis | 5777 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 43000 | - |
2 * 43000, SDS-PAGE | Candida tropicalis |
| 98000 | - |
gel filtration | Candida tropicalis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Candida tropicalis | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Candida tropicalis |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 42 | - |
- |
Candida tropicalis |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CoA + 3-oxoacyl-CoA | - |
Candida tropicalis | acyl-CoA + acetyl-CoA | - |
? | |
| CoA + 3-oxododecanoyl-CoA | - |
Candida tropicalis | acetyl-CoA + decanoyl-CoA | - |
? | |
| CoA + 3-oxohexanoyl-CoA | - |
Candida tropicalis | acetyl-CoA + butanoyl-CoA | - |
? | |
| CoA + 3-oxooctanoyl-CoA | - |
Candida tropicalis | acetyl-CoA + hexanoyl-CoA | - |
? | |
| CoA + 3-oxopentanoyl-CoA | - |
Candida tropicalis | acetyl-CoA + propanoyl-CoA | - |
? | |
| CoA + acetoacetyl-CoA | - |
Candida tropicalis | acetyl-CoA + acetyl-CoA | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 43000, SDS-PAGE | Candida tropicalis |
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