Cloned (Comment) | Organism |
---|---|
mice are transduced with adenoviruses expressing either murine mtGPAT or a catalytically inactive variant of the enzyme. Overexpressing mtGPAT results in massive 12- and 7-fold accumulation of liver triacylglycerol and diacylglycerol | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Mus musculus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q61586 | precursor | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | hypothesis: increased hepatic mtGPAT activity associated with obesity and insulin resistance contributes to increased triacylglycerol biosynthesis and inhibition of fatty acid oxidation, responses that would promote hepatic steatosis and dyslipidemia | Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
mtGPAT | - |
Mus musculus |