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Literature summary for 2.3.1.135 extracted from

  • Mondal, M.S.; Ruiz, A.; Bok, D.; Rando, R.R.
    Lecithin retinol acyltransferase contains cysteine residues essential for catalysis (2000), Biochemistry, 39, 5215-5220.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in HEK-293T cells Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
additional information mutant C161S is not significantly inactivated by N-Boc-L-biocytinyl-11-aminoundecan chloromethylketone Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00034
-
all-trans-retinol with dipalmitoylphosphatidylcholine, C182A mutant Homo sapiens
0.00047
-
all-trans-retinol with dipalmitoylphosphatidylcholine, C161S mutant Homo sapiens
0.00051
-
all-trans-retinol with dipalmitoylphosphatidylcholine, C208A mutant Homo sapiens
0.00082
-
all-trans-retinol with dipalmitoylphosphatidylcholine, C168S mutant Homo sapiens
0.00094
-
all-trans-retinol with dipalmitoylphosphatidylcholine, cloned enzyme, expressed in HEK-296T cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dipalmitoylphosphatidylcholine + all-trans-retinol mechanistic hypothesis Homo sapiens all-trans-retinyl palmitate + 2-palmitoylglycerophosphocholine
-
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