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Literature summary for 2.3.1.13 extracted from

  • James, M.O.; Bend, J.R.
    A radiochemical assay for glycine N-acyltransferase activity. Some properties of the enzyme in rat and rabbit (1978), Biochem. J., 172, 285-291.
    View publication on PubMedView publication on EuropePMC

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.15
-
phenylacetyl-CoA cosubstrate glycine Oryctolagus cuniculus
20
-
glycine acyl donor phenylacetyl-CoA Oryctolagus cuniculus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion kidney enzyme is located in the matrix, probably not membrane bound Rattus norvegicus 5739
-
mitochondrion kidney enzyme is located in the matrix, probably not membrane bound Oryctolagus cuniculus 5739
-

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
New Zealand white rabbits
-
Rattus norvegicus
-
Sprague-Dawley rats
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
Rattus norvegicus
-
kidney
-
Oryctolagus cuniculus
-
liver
-
Rattus norvegicus
-
liver
-
Oryctolagus cuniculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [┬Ámol/min/mg] Specific Activity Maximum [┬Ámol/min/mg] Comment Organism
0.105
-
activity in 176000 g supernantant of Triton X-100 solubilized preparations Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + glycine phenylacetyl-CoA acts as acyl donor Rattus norvegicus CoA + N-acylglycine
-
?
acyl-CoA + glycine phenylacetyl-CoA acts as acyl donor Oryctolagus cuniculus CoA + N-acylglycine
-
?
phenylacetyl-CoA + glycine
-
Oryctolagus cuniculus CoA + N-phenylacetylglycine
-
?

Temperature Optimum [┬░C]

Temperature Optimum [┬░C] Temperature Optimum Maximum [┬░C] Comment Organism
37
-
assay at Rattus norvegicus
37
-
assay at Oryctolagus cuniculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.8 9.5 kidney enzyme Oryctolagus cuniculus

pH Range

pH Minimum pH Maximum Comment Organism
8 10 approx. 35% of maximal activity at pH 8.0, approx. 40% of maximal activity at pH 10.0, kidney enzyme Oryctolagus cuniculus