Protein Variants | Comment | Organism |
---|---|---|
additional information | in an mec-12(e1607) background, i.e. a putative null mutant, acetylation of microtubules is absent in all developmental stages | Caenorhabditis elegans |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Caenorhabditis elegans | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Synonyms | Comment | Organism |
---|---|---|
elongator | - |
Caenorhabditis elegans |
General Information | Comment | Organism |
---|---|---|
physiological function | elongator, a GTPase component of the hyperphosphorylated holoenzyme RNA polymerase II, is a regulator of alpha-tubulin acetylation in vivo. Elongator is important for microtubule function in correct loading and velocity of vesicles in vivo, and acetylation has a function in fine-tuning intrinsic dynamics of microtubules by modulating alpha-tubulin turnover | Caenorhabditis elegans |