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Literature summary for 2.2.1.7 extracted from

  • Zhou, W.; Huang, F.; Li, S.; Wang, Y.; Zhou, C.; Shi, M.; Wang, J.; Chen, Y.; Wang, Y.; Wang, H.; Kai, G.
    Molecular cloning and characterization of two 1-deoxy-D-xylulose-5-phosphate synthase genes involved in tanshinone biosynthesis in Salvia miltiorrhiza (2016), Mol. Breed., 36, 124 .
No PubMed abstract available

Cloned(Commentary)

Cloned (Comment) Organism
expressed in transgenic hairy root lines of Salvia miltiorrhiza Salvia miltiorrhiza

Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast
-
Salvia miltiorrhiza 9507
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
pyruvate + D-glyceraldehyde 3-phosphate Salvia miltiorrhiza
-
1-deoxy-D-xylulose 5-phosphate + CO2
-
?

Organism

Organism UniProt Comment Textmining
Salvia miltiorrhiza B4YSH1
-
-
Salvia miltiorrhiza C4NXC0
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf highest expression Salvia miltiorrhiza
-
leaf weakest expression Salvia miltiorrhiza
-
root highest expression Salvia miltiorrhiza
-
root weakest expression Salvia miltiorrhiza
-
stem
-
Salvia miltiorrhiza
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pyruvate + D-glyceraldehyde 3-phosphate
-
Salvia miltiorrhiza 1-deoxy-D-xylulose 5-phosphate + CO2
-
?

Subunits

Subunits Comment Organism
? x * 76700, SDS-PAGE Salvia miltiorrhiza
? x * 78200, SDS-PAGE Salvia miltiorrhiza

Synonyms

Synonyms Comment Organism
DXS1 isoform Salvia miltiorrhiza
DXS2 isoform Salvia miltiorrhiza

pI Value

Organism Comment pI Value Maximum pI Value
Salvia miltiorrhiza isoelectric focusing
-
6.3
Salvia miltiorrhiza isoelectric focusing
-
6.4

General Information

General Information Comment Organism
malfunction isoform DXS2 downregulation of leads to a significant decrease of tanshinone accumulation in transgenic roots Salvia miltiorrhiza
metabolism enzyme overexpression significantly enhances tanshinone accumulation in transgenic roots Salvia miltiorrhiza
metabolism enzyme overexpression significantly enhances tanshinone accumulation in transgenic roots. Isoform DXS2 is an important rate-limiting gene in the methylerythritol 4-phosphate pathway involved in tanshinone biosynthesis Salvia miltiorrhiza