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Literature summary for 2.2.1.6 extracted from

  • Vercellino, R.B.; Pandolfo, C.E.; Breccia, G.; Cantamutto, M.; Presotto, A.
    AHAS Trp574Leu substitution in Raphanus sativus L. screening, enzyme activity and fitness cost (2018), Pest Manag. Sci., 74, 1600-1607 .
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
W574L the mutation causes herbicide resistance. The mutant enzyme is over 9000fold more resistant towards metsulfuron-methyl and imazethapyr than the wild type enzyme Raphanus sativus

Inhibitors

Inhibitors Comment Organism Structure
imazethapyr
-
Raphanus sativus
metsulfuron-methyl
-
Raphanus sativus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 pyruvate Raphanus sativus
-
2-acetolactate + CO2
-
?

Organism

Organism UniProt Comment Textmining
Raphanus sativus
-
line RSBA2
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
Raphanus sativus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 pyruvate
-
Raphanus sativus 2-acetolactate + CO2
-
?

Synonyms

Synonyms Comment Organism
acetohydroxyacid synthase
-
Raphanus sativus
AHAS
-
Raphanus sativus

Cofactor

Cofactor Comment Organism Structure
FAD
-
Raphanus sativus
thiamine diphosphate
-
Raphanus sativus