Protein Variants | Comment | Organism |
---|---|---|
P197L | the mutation causes serious cross-resistance to most types of enzyme inhibitors | Arabidopsis thaliana |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-(2,3-dichlorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | - |
Arabidopsis thaliana | |
2-(2,3-difluorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | - |
Arabidopsis thaliana | |
2-(2,4-dichlorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | - |
Arabidopsis thaliana | |
2-(2,4-difluorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | - |
Arabidopsis thaliana | |
2-(2,5-dichlorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | - |
Arabidopsis thaliana | |
2-(2,5-difluorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | - |
Arabidopsis thaliana | |
2-(2-bromo-4-fluorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | - |
Arabidopsis thaliana | |
2-(2-bromophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | - |
Arabidopsis thaliana | |
2-(2-chloro-4-methylphenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | - |
Arabidopsis thaliana | |
2-(2-chlorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | - |
Arabidopsis thaliana | |
2-(3-bromo-4-fluorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | - |
Arabidopsis thaliana | |
2-(3-chlorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | - |
Arabidopsis thaliana | |
2-(4-bromo-3-methylphenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | - |
Arabidopsis thaliana | |
2-(4-chloro-2-fluorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | - |
Arabidopsis thaliana | |
2-(4-chloro-2-methylphenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | - |
Arabidopsis thaliana | |
2-(4-chloro-3-methylphenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | - |
Arabidopsis thaliana | |
2-(4-chlorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | - |
Arabidopsis thaliana | |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(2-fluoro-3-methylphenoxy)benzoic acid | - |
Arabidopsis thaliana | |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(2-fluoro-4-methylphenoxy)benzoic acid | - |
Arabidopsis thaliana | |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(2-fluoro-5-methylphenoxy)benzoic acid | - |
Arabidopsis thaliana | |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(2-fluorophenoxy)benzoic acid | - |
Arabidopsis thaliana | |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(3-fluorophenoxy)benzoic acid | - |
Arabidopsis thaliana | |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(3-methylphenoxy)benzoic acid | - |
Arabidopsis thaliana | |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(4-fluorophenoxy)benzoic acid | - |
Arabidopsis thaliana | |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(4-methylphenoxy)benzoic acid | - |
Arabidopsis thaliana | |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(naphthalen-2-yloxy)benzoic acid | - |
Arabidopsis thaliana | |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-phenoxybenzoic acid | - |
Arabidopsis thaliana | |
2-[([1,1'-biphenyl]-4-yl)oxy]-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | - |
Arabidopsis thaliana | |
bispyribac | - |
Arabidopsis thaliana | |
chlorsulfuron | - |
Arabidopsis thaliana | |
flumetsulam | - |
Arabidopsis thaliana | |
imazaquin | - |
Arabidopsis thaliana | |
propoxycarbazone | - |
Arabidopsis thaliana | |
pyriftalid | - |
Arabidopsis thaliana | |
tribenuron-methyl | - |
Arabidopsis thaliana |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 pyruvate | Arabidopsis thaliana | - |
2-acetolactate + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 pyruvate | - |
Arabidopsis thaliana | 2-acetolactate + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
acetohydroxyacid synthase | - |
Arabidopsis thaliana |
AHAS | - |
Arabidopsis thaliana |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000054 | - |
bispyribac | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00008 | - |
tribenuron-methyl | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00053 | - |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(2-fluoro-3-methylphenoxy)benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00134 | - |
2-(4-chloro-3-methylphenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00141 | - |
2-(4-bromo-3-methylphenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00159 | - |
2-(2-chloro-4-methylphenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00179 | - |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(naphthalen-2-yloxy)benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00184 | - |
2-(3-chlorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00201 | - |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(3-fluorophenoxy)benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00212 | - |
2-(2,4-dichlorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00247 | - |
bispyribac | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00271 | - |
2-[([1,1'-biphenyl]-4-yl)oxy]-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00317 | - |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(naphthalen-2-yloxy)benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00325 | - |
2-(4-chloro-2-methylphenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00334 | - |
2-(4-bromo-3-methylphenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00335 | - |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(2-fluoro-3-methylphenoxy)benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00369 | - |
2-[([1,1'-biphenyl]-4-yl)oxy]-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0037 | - |
2-(2-chloro-4-methylphenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0042 | - |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-phenoxybenzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00451 | - |
2-(4-chlorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00458 | - |
2-(2-bromo-4-fluorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00537 | - |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(2-fluoro-5-methylphenoxy)benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00572 | - |
2-(2,5-difluorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00607 | - |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(2-fluoro-4-methylphenoxy)benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00642 | - |
2-(4-chloro-3-methylphenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00645 | - |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(3-methylphenoxy)benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00694 | - |
2-(3-bromo-4-fluorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00758 | - |
2-(2,4-dichlorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00827 | - |
2-(2-chlorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.00916 | - |
2-(4-chloro-2-methylphenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0119 | - |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(4-fluorophenoxy)benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0144 | - |
2-(2,5-dichlorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0147 | - |
2-(2,4-difluorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0157 | - |
2-(4-chloro-2-fluorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0158 | - |
2-(2,3-difluorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0178 | - |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(4-methylphenoxy)benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0189 | - |
2-(4-chloro-2-fluorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0201 | - |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(3-methylphenoxy)benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0202 | - |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(2-fluoro-4-methylphenoxy)benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0214 | - |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(4-fluorophenoxy)benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0234 | - |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(4-methylphenoxy)benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0257 | - |
2-(2-bromophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0263 | - |
2-(2,5-difluorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0274 | - |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(2-fluorophenoxy)benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0434 | - |
2-(3-chlorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.047 | - |
2-(2-bromo-4-fluorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0528 | - |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-phenoxybenzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0553 | - |
2-(2,5-dichlorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.056 | - |
2-(4-chlorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0605 | - |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(3-fluorophenoxy)benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0612 | - |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(2-fluoro-5-methylphenoxy)benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0657 | - |
2-(2-bromophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0757 | - |
2-(2,3-dichlorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0843 | - |
2-(2,4-difluorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.0929 | - |
2-(2,3-dichlorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | wild type enzyme, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.108 | - |
2-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]-6-(2-fluorophenoxy)benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.145 | - |
2-(3-bromo-4-fluorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.212 | - |
2-(2-chlorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.212 | - |
tribenuron-methyl | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana | |
0.228 | - |
2-(2,3-difluorophenoxy)-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)oxy]benzoic acid | mutant enzyme P197L, pH and temperature not specified in the publication | Arabidopsis thaliana |