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Literature summary for 2.2.1.6 extracted from

  • McDonald, R.A.; Satyanarayana, T.; Kaplan, J.G.
    Biosynthesis of branched-chain amino acids in Schizosaccharomyces pombe: properties of acetohydroxy acid synthetase (1973), J. Bacteriol., 114, 332-340.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
Ile less potent, noncompetitive Schizosaccharomyces pombe
Val feed-back inhibition; noncompetitive Schizosaccharomyces pombe

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ can substitute for Mg2+ Schizosaccharomyces pombe

Organism

Organism UniProt Comment Textmining
Schizosaccharomyces pombe
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Schizosaccharomyces pombe

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pyruvate
-
Schizosaccharomyces pombe 2-acetolactate + CO2
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.3 6.6
-
Schizosaccharomyces pombe

pH Range

pH Minimum pH Maximum Comment Organism
6 6.9 pH 6.0: about 50% of maximal activity, pH 6.9: about 30% of maximal activity Schizosaccharomyces pombe