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Literature summary for 2.2.1.1 extracted from

  • Kochetov, G.A.; Solovjeva, O.N.
    Structure and functioning mechanism of transketolase (2014), Biochim. Biophys. Acta, 1844, 1608-1618.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ can replace Mg2+ Saccharomyces cerevisiae
Mg2+ required Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-fructose 6-phosphate + D-glyceraldehyde 3-phosphate Saccharomyces cerevisiae
-
D-erythrose 4-phosphate + D-xylulose 5-phosphate
-
r
glyceraldehyde 3-phosphate + D-glyceraldehyde 3-phosphate Saccharomyces cerevisiae
-
D-xylulose 5-phosphate + D-xylulose 5-phosphate
-
r
additional information Saccharomyces cerevisiae the enzyme shows a broad substrate specificity with D-xylulose 5-phosphate, D-fructose 6-phosphate, erythrulose 4-phosphate, and sedoheptulose 7-phosphate as typical donor substrates as well as D-ribose 5-phosphate, glyceraldehyde 3-phosphate, and D-erythrose 4-phosphate as typical acceptor substrates ?
-
?
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate Saccharomyces cerevisiae
-
D-ribose 5-phosphate + D-xylulose 5-phosphate
-
r

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P23254
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-fructose 6-phosphate + D-glyceraldehyde 3-phosphate
-
Saccharomyces cerevisiae D-erythrose 4-phosphate + D-xylulose 5-phosphate
-
r
glyceraldehyde 3-phosphate + D-glyceraldehyde 3-phosphate
-
Saccharomyces cerevisiae D-xylulose 5-phosphate + D-xylulose 5-phosphate
-
r
additional information the enzyme shows a broad substrate specificity with D-xylulose 5-phosphate, D-fructose 6-phosphate, erythrulose 4-phosphate, and sedoheptulose 7-phosphate as typical donor substrates as well as D-ribose 5-phosphate, glyceraldehyde 3-phosphate, and D-erythrose 4-phosphate as typical acceptor substrates Saccharomyces cerevisiae ?
-
?
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
Saccharomyces cerevisiae D-ribose 5-phosphate + D-xylulose 5-phosphate
-
r

Cofactor

Cofactor Comment Organism Structure
thiamine diphosphate
-
Saccharomyces cerevisiae