Application | Comment | Organism |
---|---|---|
medicine | TKTL1 gene influences total transketolase activity and cell proliferation in human nasopharyngeal carcinoma cells, suggesting that TKTL1 gene plays an important role on glycometabolism in tumors and may become a novel target for tumor gene therapy | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
TKTL1 cloned into vector pEGFP-C1-U6 | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
RNAi | inhibits expression of TKTL1, whereas total transketolase activity is dramatically downregulated and proliferation of cancer cells is significantly inhibited in CNE cells | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P51854 | - |
- |
Homo sapiens | Q9H0I9 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | in human nasopharyngeal carcinoma tissues, TKT and TKTL2 are not upregulated | Homo sapiens | - |
nasopharyngeal carcinoma cell | transketolase activity is significantly higher in nasopharyngeal carcinoma tissues than in chronic nasopharyngitis tissues. TKTL1 in human nasopharyngeal carcinoma tissues is upregulated, whereas TKT is not upregulated | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
TKT | - |
Homo sapiens |
TKTL1 | - |
Homo sapiens |
TKTL2 | - |
Homo sapiens |
transketolase-like-1 | - |
Homo sapiens |
transketolase-like-2 | - |
Homo sapiens |