Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | increased levels of TKTL1 transcript in tumors compared with their corresponding normal tissues. Positive correlation between TKTL1 protein expression in primary tumors and the number of metastatic lymph-nodes as well as the diameter of the largest metastatic area in lymph-nodes. High levels of TKTL1 transcript are a relevant phenomenon in small PTCs | Homo sapiens |
Application | Comment | Organism |
---|---|---|
medicine | TKTL1 overexpression in papillary thyroid carcinoma bigger than 1.5 cm may be considered a factor that facilitates tumor growth and progression. Significant association between TKTL1 protein expression and the presence of multifocality, bilaterality, extrathyroidal extension, vascular invasion, sclerosis, and lymph-node metastases | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Homo sapiens | 5737 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
carcinoma cell | papillary thyroid carcinoma with or without lymph-node metastases | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
TKTL1 | - |
Homo sapiens |
transketolase-like 1 | - |
Homo sapiens |