BRENDA - Enzyme Database
show all sequences of 2.2.1.1

Transketolase from human leukocytes. Isolation, properties and induction of polyclonal antibodies

Mocali, A.; Paoletti, F.; Eur. J. Biochem. 180, 213-219 (1989)

Data extracted from this reference:

General Stability
General Stability
Organism
dilution, stable to
Homo sapiens
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.63
-
D-ribose 5-phosphate
cosubstrate D-xylulose 5-phosphate
Homo sapiens
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Mg2+
requirement
Homo sapiens
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
66000
-
alpha2, 2 * 66000, SDS-PAGE
Homo sapiens
135000
-
gel filtration
Homo sapiens
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
D-xylulose 5-phosphate + D-ribose 5-phosphate
Homo sapiens
-
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
-
r
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Homo sapiens
-
-
-
Purification (Commentary)
Commentary
Organism
-
Homo sapiens
Source Tissue
Source Tissue
Commentary
Organism
Textmining
leukocyte
-
Homo sapiens
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
10.27
-
-
Homo sapiens
Storage Stability
Storage Stability
Organism
-20°C, 2 months
Homo sapiens
4°C, several weeks
Homo sapiens
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
D-fructose 6-phosphate + D-ribose 5-phosphate
40% as effective as D-xylulose 5-phosphate
486004
Homo sapiens
?
-
-
-
?
D-xylulose 5-phosphate + D-erythrose 4-phosphate
best acceptor with D-xylulose 5-phosphate as donor
486004
Homo sapiens
D-fructose 6-phosphate + D-glyceraldehyde 3-phosphate
-
-
-
r
D-xylulose 5-phosphate + D-ribose 5-phosphate
-
486004
Homo sapiens
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
-
-
r
D-xylulose 5-phosphate + D-ribose 5-phosphate
best donor with D-ribose 5-phosphate as acceptor
486004
Homo sapiens
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
-
-
r
D-xylulose 5-phosphate + D-ribose 5-phosphate
D-ribose 5-phosphate
486004
Homo sapiens
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
-
-
r
D-xylulose 5-phosphate + D-ribose 5-phosphate
D-erythrose 4-phosphate
486004
Homo sapiens
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
-
-
r
D-xylulose 5-phosphate + D-ribose 5-phosphate
catalyzes reversible transfer of a keto group between several donor and acceptor substrates
486004
Homo sapiens
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
-
-
r
D-xylulose 5-phosphate + D-ribose 5-phosphate
wide specificity for both reactants: donor substrates may be: fructose 6-phosphate
486004
Homo sapiens
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
-
-
r
additional information
no acceptors with D-xylulose 5-phosphate as donor substrate: glucose 6-phosphate
486004
Homo sapiens
?
-
-
-
-
Subunits
Subunits
Commentary
Organism
dimer
alpha2, 2 * 66000, SDS-PAGE
Homo sapiens
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
37
-
assay at
Homo sapiens
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
additional information
-
pI: 6.5-8.5 (6-8 distinct isozymes, isoelectric focusing)
Homo sapiens
8
8.5
-
Homo sapiens
pH Range
pH Minimum
pH Maximum
Commentary
Organism
7.1
9.5
about half-maximal activity at pH 7.1 and 9.5
Homo sapiens
Cofactor
Cofactor
Commentary
Organism
Structure
thiamine diphosphate
-
Homo sapiens
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
thiamine diphosphate
-
Homo sapiens
General Stability (protein specific)
General Stability
Organism
dilution, stable to
Homo sapiens
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.63
-
D-ribose 5-phosphate
cosubstrate D-xylulose 5-phosphate
Homo sapiens
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Mg2+
requirement
Homo sapiens
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
66000
-
alpha2, 2 * 66000, SDS-PAGE
Homo sapiens
135000
-
gel filtration
Homo sapiens
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
D-xylulose 5-phosphate + D-ribose 5-phosphate
Homo sapiens
-
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
-
r
Purification (Commentary) (protein specific)
Commentary
Organism
-
Homo sapiens
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
leukocyte
-
Homo sapiens
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
10.27
-
-
Homo sapiens
Storage Stability (protein specific)
Storage Stability
Organism
-20°C, 2 months
Homo sapiens
4°C, several weeks
Homo sapiens
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
D-fructose 6-phosphate + D-ribose 5-phosphate
40% as effective as D-xylulose 5-phosphate
486004
Homo sapiens
?
-
-
-
?
D-xylulose 5-phosphate + D-erythrose 4-phosphate
best acceptor with D-xylulose 5-phosphate as donor
486004
Homo sapiens
D-fructose 6-phosphate + D-glyceraldehyde 3-phosphate
-
-
-
r
D-xylulose 5-phosphate + D-ribose 5-phosphate
-
486004
Homo sapiens
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
-
-
r
D-xylulose 5-phosphate + D-ribose 5-phosphate
best donor with D-ribose 5-phosphate as acceptor
486004
Homo sapiens
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
-
-
r
D-xylulose 5-phosphate + D-ribose 5-phosphate
D-ribose 5-phosphate
486004
Homo sapiens
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
-
-
r
D-xylulose 5-phosphate + D-ribose 5-phosphate
D-erythrose 4-phosphate
486004
Homo sapiens
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
-
-
r
D-xylulose 5-phosphate + D-ribose 5-phosphate
catalyzes reversible transfer of a keto group between several donor and acceptor substrates
486004
Homo sapiens
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
-
-
r
D-xylulose 5-phosphate + D-ribose 5-phosphate
wide specificity for both reactants: donor substrates may be: fructose 6-phosphate
486004
Homo sapiens
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
-
-
-
r
additional information
no acceptors with D-xylulose 5-phosphate as donor substrate: glucose 6-phosphate
486004
Homo sapiens
?
-
-
-
-
Subunits (protein specific)
Subunits
Commentary
Organism
dimer
alpha2, 2 * 66000, SDS-PAGE
Homo sapiens
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
37
-
assay at
Homo sapiens
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
additional information
-
pI: 6.5-8.5 (6-8 distinct isozymes, isoelectric focusing)
Homo sapiens
8
8.5
-
Homo sapiens
pH Range (protein specific)
pH Minimum
pH Maximum
Commentary
Organism
7.1
9.5
about half-maximal activity at pH 7.1 and 9.5
Homo sapiens
Other publictions for EC 2.2.1.1
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
735721
Solovjeva
Substrate inhibition of transk ...
Saccharomyces cerevisiae
Biochim. Biophys. Acta
1864
280-282
2016
-
-
-
-
-
-
1
-
-
-
-
2
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
736821
Vimala
Transketolase activity modulat ...
Escherichia coli, Escherichia coli AV139
Mol. Microbiol.
100
263-277
2016
-
-
-
-
-
-
-
-
-
-
-
2
-
3
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
737175
Xu
Transketolase counteracts oxid ...
Homo sapiens
Proc. Natl. Acad. Sci. USA
113
725-734
2016
-
1
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
1
2
2
1
-
-
735401
Lukacik
High-resolution structures of ...
Lactobacillus salivarius, Lactobacillus salivarius UCC118
Acta Crystallogr. Sect. F
71
1327-1334
2015
-
-
1
1
-
-
-
-
-
1
2
-
-
6
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
1
-
-
-
-
-
-
-
1
2
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
735416
Abdoul Zabar
-
Engineering a thermostable tra ...
Geobacillus stearothermophilus
Adv. Synth. Catal.
357
1715-1720
2015
-
-
-
-
2
-
-
4
-
-
-
-
-
1
-
-
-
-
-
-
-
2
4
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
2
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
2
4
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
735938
Yi
A thermostable transketolase e ...
Geobacillus stearothermophilus
Chem. Commun. (Camb.)
51
480-483
2015
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
3
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
735956
Ali
-
Chiral polyol synthesis cataly ...
Geobacillus stearothermophilus
ChemCatChem
7
3163-3170
2015
-
-
-
-
-
1
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
736993
Khozaei
Overexpression of plastid tran ...
Arabidopsis thaliana
Plant Cell
27
432-447
2015
-
-
1
-
-
-
-
-
3
-
-
2
-
4
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
3
-
-
2
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
735708
Kochetov
Structure and functioning mech ...
Saccharomyces cerevisiae
Biochim. Biophys. Acta
1844
1608-1618
2014
-
-
-
-
-
-
-
-
-
2
-
4
-
2
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
4
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
735856
Markert
Characterization of two transk ...
Bacillus methanolicus, Bacillus methanolicus MGA3
BMC Microbiol.
14
7
2014
-
-
1
-
-
-
5
8
-
5
2
4
-
7
-
-
1
-
-
-
-
-
4
1
1
-
1
8
1
-
-
1
-
-
-
-
-
1
1
-
-
-
-
5
-
8
-
5
2
4
-
-
-
1
-
-
-
-
4
1
1
-
1
8
1
-
-
-
-
1
1
-
8
8
735415
Abdoul-Zabar
-
Thermostable transketolase fro ...
Geobacillus stearothermophilus
Adv. Synth. Catal.
355
116-128
2013
-
-
1
-
-
-
-
4
-
1
-
1
-
1
-
-
1
-
-
-
-
2
8
-
1
1
1
-
1
1
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
4
-
1
-
1
-
-
-
1
-
-
-
2
8
-
1
1
1
-
1
1
-
-
-
-
-
-
-
-
736657
Sheng
Theoretical studies on the com ...
Homo sapiens
J. Mol. Graph. Model.
39
23-28
2013
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
737020
Bi
Cloning and expression analysi ...
Cucumis sativus
Plant Physiol. Biochem.
70
512-521
2013
-
-
-
-
-
-
-
-
1
-
1
1
-
2
-
-
-
-
-
4
-
-
1
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
1
-
-
-
-
-
4
-
-
1
1
-
-
-
-
-
-
-
1
2
-
-
2
-
-
737198
Kalhori
Cloning, expression and charac ...
Saccharum officinarum
Protein J.
32
551-559
2013
-
-
1
-
-
-
-
-
-
-
1
1
-
8
-
-
1
-
-
1
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
1
-
1
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
719312
Kim
Function of the pentose phosph ...
Mus musculus
Clin. Exp. Reprod. Med.
39
58-67
2012
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
719378
Matsushika
Characterization of non-oxidat ...
Saccharomyces cerevisiae
Enzyme Microb. Technol.
51
16-25
2012
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
2
1
-
-
720609
Fullam
Structure and function of the ...
Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
Open Biology
2
110026
2012
1
-
1
1
-
-
1
3
-
1
-
-
-
4
-
-
-
-
-
-
-
-
4
1
-
-
-
-
-
-
-
1
-
-
-
1
-
1
1
1
-
-
-
1
-
3
-
1
-
-
-
-
-
-
-
-
-
-
4
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
720854
Obiol-Pardo
Diphenyl urea derivatives as i ...
Homo sapiens
PLoS ONE
7
e32276
2012
-
-
-
1
-
-
3
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
1
-
-
3
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
720982
Solovjeva
Effects of free Ca2+ on kineti ...
Saccharomyces cerevisiae
Protein J.
31
137-140
2012
-
-
-
-
-
-
-
6
-
1
-
-
-
1
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
6
-
1
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
721070
Ranoux
-
Development of screening metho ...
Escherichia coli, Saccharomyces cerevisiae
Tetrahedron Lett.
53
790-793
2012
-
2
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
718815
Meshalkina
Interaction of transketolase f ...
Homo sapiens
Biochemistry (Moscow)
76
1061-1064
2011
-
-
1
-
-
-
-
5
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
720083
Jahromi
Structural stability of E. col ...
Escherichia coli
J. Biotechnol.
155
209-216
2011
-
-
1
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
4
-
1
2
2
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
1
2
2
-
-
-
-
-
-
-
720405
Stoffel
Transketolase in Trypanosoma b ...
Trypanosoma brucei
Mol. Biochem. Parasitol.
179
1-7
2011
-
-
1
-
-
-
-
2
2
-
-
-
-
3
-
-
1
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
2
2
-
-
-
-
-
-
1
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
720494
Domain
Transketolase A, an enzyme in ...
Escherichia coli
Mol. Microbiol.
80
853-853
2011
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
1
1
-
-
720844
Hu
Revealing the functions of the ...
Rhodopseudomonas palustris
PLoS ONE
6
e28329
2011
-
-
-
-
-
-
-
-
2
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
718499
Horsham
Expression, purification, crys ...
Lactobacillus salivarius
Acta Crystallogr. Sect. F
66
899-901
2010
-
-
1
1
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
718950
Meshalkina
Isolation and properties of hu ...
Homo sapiens
Biochemistry (Moscow)
75
873-880
2010
-
-
1
-
1
-
-
2
-
1
2
-
-
3
-
-
1
-
-
-
1
2
2
1
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
1
-
-
-
-
2
-
1
2
-
-
-
-
1
-
-
1
2
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
719890
Mitschke
The crystal structure of human ...
Homo sapiens
J. Biol. Chem.
285
31559-31570
2010
-
-
1
1
-
-
-
4
-
-
-
-
-
2
-
-
-
1
-
-
2
-
1
-
-
-
-
2
-
-
-
1
-
-
-
-
-
1
1
1
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
2
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
692645
Alexander-Kaufman
Transketolase: Observations in ...
Escherichia coli, Homo sapiens
Int. J. Biochem. Cell Biol.
41
717-720
2009
-
1
-
-
-
-
1
-
-
-
1
-
-
2
-
-
1
-
-
2
-
-
1
1
-
-
-
-
-
-
-
1
-
-
-
-
1
-
1
-
-
-
-
1
-
-
-
-
1
-
-
-
-
1
-
2
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
692698
Froehlich
Is transketolase like 1 a targ ...
Homo sapiens
Invest. New Drugs
27
297-303
2009
-
1
-
-
-
-
1
-
1
-
-
-
-
2
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
695145
Oh
Detection of transketolase in ...
Rattus norvegicus
Stem Cells Dev.
18
37-46
2009
1
2
-
-
-
-
1
-
-
-
-
-
-
2
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
2
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
696070
Sayar
-
Modelling and simulation of a ...
Escherichia coli
Biochem. Eng. J.
47
1-9
2009
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
696071
Sayar
-
Process modelling and simulati ...
Escherichia coli
Biochem. Eng. J.
47
10-18
2009
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
696175
Sevostyanova
Cooperative binding of substra ...
Saccharomyces cerevisiae
Biochemistry (Moscow)
74
789-792
2009
-
-
-
-
-
-
-
6
-
2
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
6
-
2
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
696918
Matosevic
Design and characterization of ...
Escherichia coli
Biotechnol. Prog.
26
118-126
2009
-
1
1
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
699191
Wu
Anaplastic nephroblastomas exp ...
Homo sapiens
J. Clin. Pathol.
62
460-463
2009
-
1
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
699274
Chen
Overexpression of transketolas ...
Homo sapiens
J. Exp. Clin. Cancer Res.
28
43-55
2009
-
1
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
1
1
1
1
-
-
699615
Obiol-Pardo
Homology modeling of human tra ...
Homo sapiens
J. Mol. Graph. Model.
27
723-734
2009
-
-
-
1
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
699663
Zhao
Decreased transketolase activi ...
Mus musculus
J. Neurochem.
111
537-546
2009
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
700866
Willige
Subcellular localization and e ...
Craterostigma plantagineum
Planta
229
659-666
2009
-
-
-
-
-
-
-
-
2
-
-
-
-
3
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
704746
Sawada
Key role for transketolase act ...
Moniliella megachiliensis, Moniliella megachiliensis SN-G42
J. Biosci. Bioeng.
108
385-390
2009
2
1
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
685766
Lee
A novel assay system for the m ...
Escherichia coli
Biotechnol. Lett.
30
899-904
2008
-
1
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
690323
Voelker
Expression of transketolase-li ...
Homo sapiens
Am. J. Clin. Pathol.
130
50-57
2008
-
1
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
690708
Meshalkina
New evidence for cofactors ami ...
Saccharomyces cerevisiae
Biochem. Biophys. Res. Commun.
366
692-697
2008
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
1
-
-
-
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
691270
Thomas
Synthesis, in vitro and in viv ...
Homo sapiens
Bioorg. Med. Chem. Lett.
18
2206-2210
2008
-
1
-
-
-
-
1
-
-
-
-
-
-
2
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
691298
Le Huerou
Prodrug thiamine analogs as in ...
Mus musculus, Mus musculus Balb-c
Bioorg. Med. Chem. Lett.
18
505-508
2008
-
1
-
-
-
-
1
-
-
-
-
-
-
3
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
691299
Thomas
Non-charged thiamine analogs a ...
Homo sapiens
Bioorg. Med. Chem. Lett.
18
509-512
2008
-
1
-
-
-
-
4
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
1
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
691423
Aucamp
A microplate-based evaluation ...
Escherichia coli
Biotechnol. Bioeng.
99
1303-1310
2008
-
1
1
-
2
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
1
1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
691583
Zerilli
Increased expression of transk ...
Homo sapiens
Cancer
113
936-944
2008
1
1
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
691586
Zhang
Overexpression of transketolas ...
Homo sapiens
Cancer Biol. Ther.
7
517-522
2008
-
1
1
-
-
-
1
-
-
-
-
-
-
3
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
692925
Naula
A new erythrose 4-phosphate de ...
Leishmania mexicana
J. Biochem. Biophys. Methods
70
1185-1187
2008
-
1
1
-
-
-
1
1
-
1
-
-
-
2
-
-
-
-
-
-
1
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
1
1
1
-
-
-
-
1
-
1
-
1
-
-
-
-
-
-
-
-
1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
693291
Hibbert
Directed evolution of transket ...
Escherichia coli
J. Biotechnol.
134
240-245
2008
-
1
1
-
29
-
-
2
-
1
-
-
-
1
-
-
1
-
-
-
40
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
1
1
1
-
29
-
-
-
-
2
-
1
-
-
-
-
-
1
-
-
40
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
693795
Kohrenhagen
Expression of transketolase-li ...
Homo sapiens
J. Obstet. Gynaecol. Res.
34
293-300
2008
-
1
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
694066
Joshi
Molecular cloning and characte ...
Plasmodium falciparum
Mol. Biochem. Parasitol.
160
32-41
2008
-
1
1
-
-
-
1
2
2
1
1
-
-
6
-
-
1
-
-
1
-
-
1
1
-
-
-
-
-
-
-
1
1
-
-
-
1
1
1
-
-
-
-
1
1
2
2
1
1
-
-
-
-
1
-
1
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
694176
Lovato
Transketolase and CNPase I are ...
Homo sapiens
Mol. Cell. Proteomics
7
2337-2349
2008
-
1
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
694236
Harinarayanan
Synthetic growth phenotypes of ...
Escherichia coli
Mol. Microbiol.
69
882-894
2008
1
1
1
-
1
-
1
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
2
2
1
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
695034
Sevostyanova
Effect of bivalent cations on ...
Saccharomyces cerevisiae
Proteins
71
541-545
2008
-
-
-
-
-
-
-
2
-
2
-
-
-
1
-
-
1
-
-
-
1
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
2
-
-
-
-
-
1
-
-
1
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
695175
Charmantray
-
Chemoenzymatic synthesis of L- ...
Saccharomyces cerevisiae
Tetrahedron Lett.
49
3229-3233
2008
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
695423
Smith
-
Enhancing and reversing the st ...
Escherichia coli
Adv. Synth. Catal.
350
2631-2638
2008
-
-
-
-
4
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
672288
Ospanov
Influence of donor substrate o ...
Saccharomyces cerevisiae
Biochemistry
72
84-92
2007
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
690448
Hu
The TKTL1 gene influences tota ...
Homo sapiens
Anticancer Drugs
18
427-433
2007
-
1
-
-
-
-
1
-
-
-
-
-
-
2
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
690697
Yurshev
Nonequivalence of transketolas ...
Saccharomyces cerevisiae
Biochem. Biophys. Res. Commun.
361
1044-1047
2007
1
-
-
-
-
-
-
4
-
-
-
-
-
1
-
-
1
-
1
-
1
1
2
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
1
-
-
-
-
-
-
4
-
-
-
-
-
-
-
1
1
-
1
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
690883
Asztalos
Strain and near attack conform ...
Escherichia coli
Biochemistry
46
12037-12052
2007
-
-
1
1
1
-
-
-
-
1
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
1
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
691025
Ospanov
Influence of donor substrate o ...
Saccharomyces cerevisiae
Biochemistry (Moscow)
72
84-92
2007
-
-
-
-
-
-
-
-
-
2
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
691433
Miller
Optimisation and evaluation of ...
Escherichia coli
Biotechnol. Lett.
29
1759-1770
2007
1
1
1
-
-
-
1
-
-
1
-
-
-
1
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
1
1
1
1
-
-
-
-
1
-
-
-
1
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
691763
Chen
-
Modelling and optimization of ...
synthetic construct
Chem. Eng. Sci.
62
3178-3184
2007
-
1
-
-
-
-
1
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
1
-
-
-
-
1
-
1
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
692117
Martinez-Torres
-
Structural stability of E. col ...
Escherichia coli
Enzyme Microb. Technol.
41
653-662
2007
-
1
1
-
-
-
1
-
-
1
-
-
-
1
-
-
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-
1
-
-
-
-
1
1
1
-
-
-
-
1
-
-
-
1
-
-
-
-
-
1
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
692143
Voelker
Overexpression of transketolas ...
Homo sapiens
Eur. Arch. Otorhinolaryngol.
264
1431-1436
2007
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
692673
Krockenberger
Transketolase-like 1 expressio ...
Homo sapiens
Int. J. Gynecol. Cancer
17
101-106
2007
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
693289
Hibbert
Directed evolution of transket ...
Escherichia coli
J. Biotechnol.
131
425-432
2007
-
1
1
-
12
-
-
4
-
-
-
-
-
2
-
-
1
-
-
-
10
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
1
1
1
-
12
-
-
-
-
4
-
-
-
-
-
-
-
1
-
-
10
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
694217
Domain
Transketolase A, an enzyme in ...
Escherichia coli
Mol. Microbiol.
66
383-394
2007
1
1
1
-
1
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
694502
Foeldi
Transketolase protein TKTL1 ov ...
Homo sapiens
Oncol. Rep.
17
841-845
2007
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
672285
Sevostyanova
Two methods for determination ...
Saccharomyces cerevisiae
Biochemistry
71
560-562
2006
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
672550
Smith
A colorimetric assay for scree ...
Escherichia coli
Bioorg. Med. Chem.
14
7062-7065
2006
-
1
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
672632
Ospanov
Theoretical model of interacti ...
Saccharomyces cerevisiae
Biophys. Chem.
124
106-114
2006
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
675191
Boren
In situ localization of transk ...
Rattus norvegicus
J. Histochem. Cytochem.
54
191-199
2006
-
-
-
-
-
-
-
-
2
-
-
-
-
4
-
-
-
-
-
10
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
10
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
677176
Sevestre
-
Synthesis of stereochemical pr ...
Saccharomyces cerevisiae
Tetrahedron
62
3969-3976
2006
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
692208
Lonsdale
Three case reports to illustra ...
Homo sapiens
Evid. Based. Complement Alternat. Med.
4
247-250
2006
1
1
-
-
-
-
-
-
-
1
-
-
-
2
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
658678
Golbik
Effect of coenzyme modificatio ...
Saccharomyces cerevisiae
Febs J.
272
1326-1342
2005
-
-
-
1
1
-
2
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
3
-
-
-
-
9
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
9
-
-
-
-
-
-
-
-
-
-
672281
Esakova
Effect of transketolase substr ...
Saccharomyces cerevisiae
Biochemistry
70
770-776
2005
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
674081
Kochetov
Binding of the coenzyme and fo ...
Saccharomyces cerevisiae
IUBMB Life
57
491-497
2005
-
-
-
1
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
675747
Esakova
Effects of transketolase cofac ...
Saccharomyces cerevisiae
Life Sci.
78
8-13
2005
-
-
-
-
-
1
-
-
-
2
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
657667
Bobst
The role of cysteine 160 in th ...
Rhodobacter sphaeroides
Arch. Biochem. Biophys.
426
43-54
2004
-
-
-
-
4
-
-
14
-
-
2
-
-
4
1
-
1
1
-
-
5
-
1
1
-
-
-
-
4
-
-
1
-
-
-
-
-
-
1
-
4
-
-
-
-
14
-
-
2
-
-
1
-
1
-
-
5
-
1
1
-
-
-
-
4
-
-
-
-
-
-
-
-
-
657847
Veitch
Transketolase from Leishmania ...
Leishmania mexicana
Biochem. J.
382
759-767
2004
-
-
1
1
-
-
1
1
2
-
2
-
-
3
-
1
-
-
-
-
1
1
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
1
-
1
2
-
2
-
-
-
1
-
-
-
1
1
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
658646
Esakova
Donor substrate regulation of ...
Saccharomyces cerevisiae
Eur. J. Biochem.
271
4189-4194
2004
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
658741
Selivanov
Kinetic study of the H103A mut ...
Saccharomyces cerevisiae
FEBS Lett.
567
270-274
2004
-
-
-
-
1
-
-
-
-
2
-
-
-
2
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
659740
Selivanov
-
Studies of thiamin diphosphate ...
Saccharomyces cerevisiae
J. Mol. Catal. B
26
33-40
2003
-
-
-
-
-
-
-
-
-
2
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486020
Fiedler
Examination of donor substrate ...
Saccharomyces cerevisiae
J. Biol. Chem.
276
16051-16058
2001
-
-
1
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486019
Kovina
Influence of transketolase sub ...
Saccharomyces cerevisiae
Biochem. Biophys. Res. Commun.
275
968-972
2000
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
486017
Soh
-
Critical role of Arg433 in rat ...
Rattus norvegicus
Biochem. J.
333
367-372
1998
-
-
1
-
4
-
-
4
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
4
-
-
-
-
4
-
-
2
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486018
Nilsson
Asp477 is a determinant of the ...
Saccharomyces cerevisiae
FEBS Lett.
424
49-52
1998
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
6
-
-
-
-
12
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
12
-
-
-
-
-
-
-
-
-
-
486025
Schneider
Crystallography and mutagenesi ...
Escherichia coli, Saccharomyces cerevisiae
Biochim. Biophys. Acta
1385
387-398
1998
-
-
-
1
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486026
Schenk
Properties and functions of th ...
Cyberlindnera jadinii, Escherichia coli, Homo sapiens, Mus musculus, Oryctolagus cuniculus, Rattus norvegicus, Saccharomyces cerevisiae, Saccharomyces pastorianus, Spinacia oleracea, Sus scrofa
Int. J. Biochem. Cell Biol.
30
1297-1318
1998
-
-
-
-
-
1
-
21
-
-
-
-
-
11
-
-
-
-
-
6
-
-
23
-
-
-
-
-
8
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
21
-
-
-
-
-
-
-
-
-
6
-
-
23
-
-
-
-
-
8
-
-
-
-
-
-
-
-
-
486015
Nilsson
Examination of substrate bindi ...
Saccharomyces cerevisiae
J. Biol. Chem.
272
1864-1869
1997
-
-
-
1
4
-
-
15
-
-
1
-
-
2
-
-
-
-
-
-
-
-
1
1
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
1
4
-
-
-
-
15
-
-
1
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
4
-
-
-
-
-
-
-
-
-
486016
Wikner
Identification of catalyticall ...
Saccharomyces cerevisiae
Biochemistry
36
15643-15649
1997
-
-
-
-
7
-
-
19
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
-
7
-
-
-
-
19
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
6
-
-
-
-
-
-
-
-
-
486024
Gyamerah
-
Kinetics of overexpressed tran ...
Escherichia coli
Enzyme Microb. Technol.
20
127-134
1997
-
-
1
-
-
-
1
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486021
Flechner
Molecular characterization of ...
Spinacia oleracea
Plant Mol. Biol.
32
475-484
1996
-
-
1
-
-
-
-
-
1
-
-
-
-
7
-
-
1
-
-
-
1
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
1
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
486014
Meshalkina
The presence of a hydroxyl gro ...
Saccharomyces cerevisiae
FEBS Lett.
375
220-222
1995
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486023
Sprenger
Transketolase A of Escherichia ...
Escherichia coli
Eur. J. Biochem.
230
525-532
1995
-
-
-
-
-
-
2
11
-
2
2
1
-
4
-
-
1
-
-
-
1
-
11
1
1
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
2
-
11
-
2
2
1
-
-
-
1
-
-
1
-
11
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
486000
Demuynck
-
Immunoaffinity purification of ...
Saccharomyces cerevisiae, Spinacia oleracea
Agric. Biol. Chem.
54
3073-3078
1990
-
-
-
-
-
-
2
-
-
2
2
2
-
2
-
-
2
-
-
1
2
-
6
3
-
-
-
-
2
-
-
2
-
-
-
-
-
-
2
-
-
-
-
2
-
-
-
2
2
2
-
-
-
2
-
1
2
-
6
3
-
-
-
-
2
-
-
-
-
-
-
-
-
-
2239
Teige
Purification, properties and i ...
Spinacia oleracea
Eur. J. Biochem.
252
237-244
1989
-
-
-
-
-
-
-
2
1
-
2
-
-
5
-
-
1
-
-
-
1
-
1
1
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
1
-
2
-
-
-
-
1
-
-
1
-
1
1
-
-
-
2
-
-
-
-
-
-
-
-
-
-
486004
Mocali
Transketolase from human leuko ...
Homo sapiens
Eur. J. Biochem.
180
213-219
1989
-
-
-
-
-
1
-
1
-
1
2
1
-
3
-
-
1
-
-
2
1
2
9
1
1
-
-
-
2
1
-
1
-
-
-
-
-
-
1
-
-
1
-
-
-
1
-
1
2
1
-
-
-
1
-
2
1
2
9
1
1
-
-
-
2
1
-
-
-
-
-
-
-
-
486010
Kuimov
Inhibition of transketolase by ...
Saccharomyces cerevisiae
Biochem. Int.
17
517-521
1989
-
-
-
-
-
-
1
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486011
Masri
Isolation of transketolase fro ...
Oryctolagus cuniculus
Comp. Biochem. Physiol. B
90
167-172
1988
-
-
-
-
-
-
-
3
-
-
1
1
-
2
-
-
1
-
-
2
-
-
4
-
1
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
3
-
-
1
1
-
-
-
1
-
2
-
-
4
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
486006
Takeuchi
Purification and characterizat ...
Homo sapiens
Biochim. Biophys. Acta
872
24-32
1986
2
-
-
-
-
2
4
1
-
1
2
-
-
2
-
-
1
-
-
2
1
1
-
1
1
-
2
-
2
1
-
1
-
-
-
2
-
-
1
-
-
2
-
4
-
1
-
1
2
-
-
-
-
1
-
2
1
1
-
1
1
-
2
-
2
1
-
-
-
-
-
-
-
-
486007
Paoletti
Immunoaffinity purification of ...
Rattus norvegicus
Arch. Biochem. Biophys.
245
212-219
1986
-
-
-
-
-
1
1
2
1
-
2
1
-
3
-
-
1
-
-
2
-
3
1
1
2
-
-
-
1
1
1
1
-
-
-
-
-
-
1
-
-
1
-
1
-
2
1
-
2
1
-
-
-
1
-
2
-
3
1
1
2
-
-
-
1
1
1
-
-
-
-
-
-
-
486008
Paoletti
Purification and properties of ...
Rattus norvegicus
Arch. Biochem. Biophys.
222
489-496
1983
-
-
-
-
-
-
1
1
-
-
2
1
-
2
-
-
1
-
-
2
-
2
6
1
1
-
-
-
1
1
-
1
-
-
-
-
-
-
1
-
-
-
-
1
-
1
-
-
2
1
-
-
-
1
-
2
-
2
6
1
1
-
-
-
1
1
-
-
-
-
-
-
-
-
485998
Kochetov
Determination of transketolase ...
Saccharomyces cerevisiae
Methods Enzymol.
89
43-44
1982
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486001
Murphy
The properties from transketol ...
Spinacia oleracea, Triticum aestivum
Planta
155
316-320
1982
-
-
-
-
-
-
-
-
4
2
2
2
-
5
-
-
2
-
2
2
1
-
10
4
-
-
-
-
4
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
4
2
2
2
-
-
-
2
2
2
1
-
10
4
-
-
-
-
4
-
-
-
-
-
-
-
-
-
486002
Kochetov
Transketolase from yeast, rat ...
Rattus norvegicus, Saccharomyces cerevisiae, Sus scrofa
Methods Enzymol.
90
209-223
1982
-
-
-
1
-
-
3
3
3
6
3
3
-
6
-
-
3
-
-
5
3
3
27
2
-
-
4
-
7
-
2
3
-
-
-
-
-
-
3
1
-
-
-
3
-
3
3
6
3
3
-
-
-
3
-
5
3
3
27
2
-
-
4
-
7
-
2
-
-
-
-
-
-
-
486005
Warnock
The isolation and preliminary ...
Homo sapiens
Biochem. Biophys. Res. Commun.
106
719-723
1982
-
-
-
-
-
-
-
3
-
1
-
1
-
1
-
-
1
-
-
1
-
2
1
-
1
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
3
-
1
-
1
-
-
-
1
-
1
-
2
1
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
486009
Schellenberg
Transketolase from human red b ...
Homo sapiens
Methods Enzymol.
90
223-228
1982
-
-
-
-
-
-
-
-
-
1
1
1
-
2
-
-
1
-
-
1
1
1
1
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
1
1
-
-
-
1
-
1
1
1
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486012
Blass
Kinetic studies of mouse brain ...
Mus musculus
J. Neurochem.
39
729-733
1982
-
-
-
-
-
-
-
3
-
-
-
-
-
2
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
485999
Egan
Transketolase kinetics. The sl ...
Saccharomyces cerevisiae
J. Biol. Chem.
256
4877-4883
1981
-
-
-
-
-
-
1
1
-
2
-
1
-
1
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
1
-
1
-
2
-
1
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
486003
Philippov
Characterization and propertie ...
Sus scrofa
Biochim. Biophys. Acta
613
359-369
1980
-
-
-
-
-
-
-
-
-
1
3
-
-
2
-
-
1
-
-
2
1
1
-
1
2
-
3
-
2
-
2
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
3
-
-
-
-
1
-
2
1
1
-
1
2
-
3
-
2
-
2
-
-
-
-
-
-
-
485995
Klein
Purification and properties of ...
Cyberlindnera jadinii
Hoppe-Seyler's Z. Physiol. Chem.
358
1325-1337
1977
-
-
-
-
-
1
3
1
-
1
2
1
-
2
-
-
1
-
-
-
1
-
1
1
1
-
-
-
2
1
3
1
-
-
-
-
-
-
1
-
-
1
-
3
-
1
-
1
2
1
-
-
-
1
-
-
1
-
1
1
1
-
-
-
2
1
3
-
-
-
-
-
-
-
485996
Kochetov
Kinetics of reconstruction of ...
Saccharomyces cerevisiae
FEBS Lett.
53
211-212
1975
-
-
-
-
-
-
-
-
-
1
-
1
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
485997
Saitou
The purification and some prop ...
Saccharomyces pastorianus
FEBS Lett.
40
114-118
1974
-
-
-
-
-
-
2
-
-
1
2
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
1
2
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486013
Heinrich
Transketolase from human eryth ...
Homo sapiens
Helv. Chim. Acta
54
2658-2668
1971
-
-
-
-
-
-
-
-
-
-
1
-
-
2
-
-
1
-
-
2
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
485992
Domagk
-
Fructose ane erythrose metabol ...
Alcaligenes faecalis
Arch. Biochem. Biophys.
109
342-349
1965
-
-
-
-
-
-
-
-
-
1
-
1
-
1
-
-
1
-
-
-
1
1
2
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
1
-
-
-
1
-
-
1
1
2
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
485991
Racker
-
Transketolase ...
Cyberlindnera jadinii, Lactobacillus pentosus, Oryctolagus cuniculus, Saccharomyces cerevisiae, Saccharomyces pastorianus, Spinacia oleracea
The Enzymes, 2nd Ed. (Boyer, P. D. , Lardy, H. , Myrbäck, K. , eds. )
5
397-406
1961
-
-
-
1
-
-
1
5
8
6
1
6
-
6
-
-
-
-
-
2
1
7
91
-
-
-
-
2
1
-
-
6
-
-
-
-
-
-
6
1
-
-
-
1
-
5
8
6
1
6
-
-
-
-
-
2
1
7
91
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
485993
Horecker
The role of xylulose 5-phospha ...
Rattus norvegicus, Spinacia oleracea
J. Biol. Chem.
223
1009-1019
1956
-
-
-
-
-
-
-
-
-
2
-
2
-
2
-
-
1
-
-
2
-
2
14
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
2
-
-
-
1
-
2
-
2
14
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
485994
De La Haba
Crystalline transketolase from ...
Saccharomyces cerevisiae
J. Biol. Chem.
214
409-426
1955
-
-
-
1
-
-
-
-
-
1
-
1
-
2
-
-
1
-
-
-
-
2
14
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
1
-
1
-
-
-
1
-
-
-
2
14
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-