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Literature summary for 2.1.4.1 extracted from

  • Braissant, O.; Bachmann, C.; Henry, H.
    Expression and function of AGAT, GAMT and CT1 in the mammalian brain (2007), Subcell. Biochem., 46, 67-81.
    View publication on PubMed
Search for more literature for 2.1.4.1

Application

Application Comment Organism
medicine creatine deficiency syndromes, either due to AGAT, GAMT or SLC6A8 deficiencies, lead to a complete absence, or a very strong decrease, of creatine within the brain Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-arginine + glycine Rattus norvegicus
-
 L-ornithine + guanidinoacetate
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
astrocyte adult brain Rattus norvegicus
-
brain
-
 Rattus norvegicus
-
central nervous system
-
 Rattus norvegicus
-
choroid plexus adult brain Rattus norvegicus
-
endothelial cell microcapillary endothelial cell, adult brain Rattus norvegicus
-
epithelium ependymal epithelium, adult brain, developing embryonic brain Rattus norvegicus
-
forebrain developing embryonic brain Rattus norvegicus
-
hindbrain developing embryonic brain Rattus norvegicus
-
kidney
-
 Rattus norvegicus
-
liver
-
 Rattus norvegicus
-
midbrain developing embryonic brain Rattus norvegicus
-
neuron adult brain Rattus norvegicus
-
oligodendrocyte adult brain Rattus norvegicus
-
pancreas
-
 Rattus norvegicus
-
spinal cord developing embryonic brain Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arginine + glycine
-
 Rattus norvegicus L-ornithine + guanidinoacetate
-
 ?

Synonyms

Synonyms Comment Organism
AGAT
-
 Rattus norvegicus
arginine:glycine amidinotransferase
-
 Rattus norvegicus
glycine amidinotransferase
-
 Rattus norvegicus