Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of the putrescine-producing strain PUT1 by deletion of argF, the gene for ornithine transcarbamoylase, and argR, encoding the L-arginine repressor, combined with heterologous expression of the Escherichia coli gene for L-ornithine decarboxylase SpeC. The strain requires supplementation of L-arginine and shows growth-decoupled putrescine production. By fine-tuning argF expression through modifications of the promoter, the translational start codon and/or the ribosome binding site, high productivity and titer can be obtained, optimization of putrescine production by mutant strains, overview | Corynebacterium glutamicum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
carbamoyl phosphate + L-ornithine | Corynebacterium glutamicum | - |
L-citrulline + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Corynebacterium glutamicum | - |
gene argF | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
carbamoyl phosphate + L-ornithine | - |
Corynebacterium glutamicum | L-citrulline + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ArgF | - |
Corynebacterium glutamicum |
ornithine transcarbamoylase | - |
Corynebacterium glutamicum |
OTC | - |
Corynebacterium glutamicum |
General Information | Comment | Organism |
---|---|---|
metabolism | ArgF is involved in the biosynthesis of L-arginine, overview | Corynebacterium glutamicum |