Crystallization (Comment) | Organism |
---|---|
hanging drop vapor diffusion method, crystal structures of Mtb OTC in orthorhombic and hexagonal form hexagonal form crystals complexed with carbamoyl phosphate and L-norvaline | Mycobacterium tuberculosis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
L-norvaline | competitive | Mycobacterium tuberculosis |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
33000 | - |
3 * 33000, crystal structure analysis | Mycobacterium tuberculosis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
carbamoyl phosphate + L-ornithine | Mycobacterium tuberculosis | catalyzes the sixth step in arginine biosynthesis | phosphate + citrulline | - |
r | |
carbamoyl phosphate + L-ornithine | Mycobacterium tuberculosis H37Rv | catalyzes the sixth step in arginine biosynthesis | phosphate + citrulline | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | P9WIT9 | - |
- |
Mycobacterium tuberculosis H37Rv | P9WIT9 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
carbamoyl phosphate + L-ornithine | catalyzes the sixth step in arginine biosynthesis | Mycobacterium tuberculosis | phosphate + citrulline | - |
r | |
carbamoyl phosphate + L-ornithine | catalyzes the sixth step in arginine biosynthesis | Mycobacterium tuberculosis H37Rv | phosphate + citrulline | - |
r |
Subunits | Comment | Organism |
---|---|---|
hexamer | crystal structure analysis, possibly a crystallization artifact | Mycobacterium tuberculosis |
trimer | 3 * 33000, crystal structure analysis | Mycobacterium tuberculosis |
Synonyms | Comment | Organism |
---|---|---|
Mtb OTC | - |
Mycobacterium tuberculosis |