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Literature summary for 2.1.3.2 extracted from

  • Zhang, Y.; Kantrowitz, E.R.
    The synergistic inhibition of Escherichia coli aspartate carbamoyltransferase by UTP in the presence of CTP is due to the binding of UTP to the low affinity CTP sites (1991), J. Biol. Chem., 266, 22154-22158.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
D19A loss of the synergistic inhibition of UTP in the presence of CTP Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
CTP synergistic inhibition by CTP and UTP Escherichia coli
UTP synergistic inhibition by CTP and UTP, no inhibition unless CTP is present Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
carbamoylphosphate + L-aspartate Escherichia coli
-
phosphate + N-carbamoyl-L-aspartate
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
carbamoyl phosphate + L-aspartate
-
Escherichia coli phosphate + N-carbamoyl-L-aspartate
-
?
carbamoylphosphate + L-aspartate
-
Escherichia coli phosphate + N-carbamoyl-L-aspartate
-
?