Cloned (Comment) | Organism |
---|---|
into the plasmid pMH4 for expression in the Escherichia coli strain GeneHogs | Thermotoga maritima |
Crystallization (Comment) | Organism |
---|---|
the three-dimensional structure of TM1249 is determined to 1.88 A resolution by molecular replacement | Thermotoga maritima |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
K+ | the refined structure includes two K+ ions in the asymmetric unit | Thermotoga maritima |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
49700 | - |
monomer, residues 1-452 | Thermotoga maritima |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | Thermotoga maritima | - |
tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Thermotoga maritima | - |
- |
- |
Purification (Comment) | Organism |
---|---|
using a nickel-chelating resin and a Resource Q column | Thermotoga maritima |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | - |
Thermotoga maritima | tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | - |
Thermotoga maritima |
Synonyms | Comment | Organism |
---|---|---|
5-aminoimidazole-4-carboxamide ribonucleotide transformylase | - |
Thermotoga maritima |
AICAR TFase | - |
Thermotoga maritima |
AICAR transformylase | - |
Thermotoga maritima |
PurH | - |
Thermotoga maritima |
TM1249 | - |
Thermotoga maritima |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
10-formyltetrahydrofolate | - |
Thermotoga maritima |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Thermotoga maritima | calculated isoelectric point | - |
5.49 |