BRENDA - Enzyme Database
show all sequences of 2.1.2.2

Involvement of a transformylase enzyme in siderophore synthesis in Pseudomonas aeruginosa

McMorran, B.J.; Kumara, H.M.C.S.; Sullivan, K.; Lamont, I.L.; Microbiology 147, 1517-1524 (2001)

Data extracted from this reference:

Cloned(Commentary)
Cloned (Commentary)
Organism
; pvdF gene characterization
Pseudomonas aeruginosa
Engineering
Protein Variants
Commentary
Organism
additional information
enzyme disruption mutant, no synthesis of pyoverdine, mutant strain is unable to grow on King´s B agar containing iron-chelating agent EDTA
Pseudomonas aeruginosa
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Fe2+
expression regulated by amount of iron in the growth medium
Pseudomonas aeruginosa
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
30985
-
x * 30985, calculated
Pseudomonas aeruginosa
31000
-
DNA sequencing
Pseudomonas aeruginosa
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
Drosophila melanogaster
-
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
Bacillus subtilis
-
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
Saccharomyces cerevisiae
-
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
Arabidopsis thaliana
-
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
-
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
Pseudomonas aeruginosa
involved in pyoverdine synthesis
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
?
Organism
Organism
UniProt
Commentary
Textmining
Arabidopsis thaliana
-
-
-
Bacillus subtilis
-
-
-
Drosophila melanogaster
-
fruit fly
-
Escherichia coli
-
-
-
Pseudomonas aeruginosa
-
-
-
Saccharomyces cerevisiae
-
yeast
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
485736
Drosophila melanogaster
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
-
?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
485736
Drosophila melanogaster
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
485736
Drosophila melanogaster
?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
485736
Bacillus subtilis
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
-
?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
485736
Bacillus subtilis
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
485736
Bacillus subtilis
?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
485736
Escherichia coli
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
-
-
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
485736
Saccharomyces cerevisiae
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
-
?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
485736
Saccharomyces cerevisiae
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
485736
Saccharomyces cerevisiae
?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
485736
Arabidopsis thaliana
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
-
-
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
485736
Pseudomonas aeruginosa
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
485736
Pseudomonas aeruginosa
?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
involved in pyoverdine synthesis
485736
Pseudomonas aeruginosa
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
-
?
10-formyltetrahydrofolate + N5-hydroxyornithine
-
485736
Pseudomonas aeruginosa
tetrahydrofolate + N2-formyl-N5-hydroxyornithine
-
-
-
?
10-formyltetrahydrofolate + N5-hydroxyornithine
-
485736
Pseudomonas aeruginosa
tetrahydrofolate + N5-formyl-N5-hydroxyornithine
-
-
-
?
Subunits
Subunits
Commentary
Organism
?
x * 30985, calculated
Pseudomonas aeruginosa
Synonyms
Synonyms
Commentary
Organism
GART synthetase
-
Arabidopsis thaliana
GART synthetase
-
Bacillus subtilis
GART synthetase
-
Drosophila melanogaster
GART synthetase
-
Escherichia coli
GART synthetase
-
Saccharomyces cerevisiae
Cloned(Commentary) (protein specific)
Commentary
Organism
; pvdF gene characterization
Pseudomonas aeruginosa
Engineering (protein specific)
Protein Variants
Commentary
Organism
additional information
enzyme disruption mutant, no synthesis of pyoverdine, mutant strain is unable to grow on King´s B agar containing iron-chelating agent EDTA
Pseudomonas aeruginosa
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Fe2+
expression regulated by amount of iron in the growth medium
Pseudomonas aeruginosa
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
30985
-
x * 30985, calculated
Pseudomonas aeruginosa
31000
-
DNA sequencing
Pseudomonas aeruginosa
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
Drosophila melanogaster
-
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
Bacillus subtilis
-
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
Saccharomyces cerevisiae
-
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
Arabidopsis thaliana
-
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
-
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
Pseudomonas aeruginosa
involved in pyoverdine synthesis
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
485736
Drosophila melanogaster
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
-
?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
485736
Drosophila melanogaster
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
485736
Drosophila melanogaster
?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
485736
Bacillus subtilis
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
-
?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
485736
Bacillus subtilis
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
485736
Bacillus subtilis
?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
485736
Escherichia coli
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
-
-
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
485736
Saccharomyces cerevisiae
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
-
?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
485736
Saccharomyces cerevisiae
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
485736
Saccharomyces cerevisiae
?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
485736
Arabidopsis thaliana
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
-
-
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
-
485736
Pseudomonas aeruginosa
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
485736
Pseudomonas aeruginosa
?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide
involved in pyoverdine synthesis
485736
Pseudomonas aeruginosa
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide
-
-
-
?
10-formyltetrahydrofolate + N5-hydroxyornithine
-
485736
Pseudomonas aeruginosa
tetrahydrofolate + N2-formyl-N5-hydroxyornithine
-
-
-
?
10-formyltetrahydrofolate + N5-hydroxyornithine
-
485736
Pseudomonas aeruginosa
tetrahydrofolate + N5-formyl-N5-hydroxyornithine
-
-
-
?
Subunits (protein specific)
Subunits
Commentary
Organism
?
x * 30985, calculated
Pseudomonas aeruginosa
Other publictions for EC 2.1.2.2
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
736059
Liu
Synthesis and antitumor activi ...
Homo sapiens
Eur. J. Med. Chem.
93
142-155
2015
-
-
-
-
-
-
10
-
-
-
-
-
-
1
-
-
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3
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2
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10
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3
-
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-
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-
736619
Wang
Novel 5-substituted pyrrolo[2, ...
Homo sapiens
J. Med. Chem.
58
1479-1493
2015
-
-
-
-
-
-
15
-
-
-
-
-
-
2
-
-
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-
1
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-
2
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15
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1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
736225
Cong
Increased expression of glycin ...
Homo sapiens
Hum. Pathol.
45
1370-1378
2014
-
1
1
-
1
-
-
-
-
-
-
-
-
2
-
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-
5
-
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-
2
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-
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-
1
1
-
-
1
-
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-
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
3
3
-
-
-
736945
Liu
Glycinamide ribonucleotide for ...
Homo sapiens
Pathol. Res. Pract.
210
256-263
2014
-
1
-
-
1
-
-
-
-
1
-
-
-
1
-
-
-
-
-
5
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
2
2
-
-
-
745966
Liu
Glycinamide ribonucleotide fo ...
Homo sapiens
Pathol. Res. Pract.
210
256-263
2014
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
-
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
735672
Connelly
Biological and structural eval ...
Homo sapiens
Biochemistry
52
5133-5144
2013
-
-
1
1
-
-
11
-
-
-
-
-
-
2
-
-
1
-
-
1
-
-
1
-
2
-
-
-
-
-
-
-
1
5
-
-
-
-
1
1
1
-
-
-
11
5
-
-
-
-
-
-
-
-
1
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
736610
Mitchell-Ryan
Discovery of 5-substituted pyr ...
Homo sapiens
J. Med. Chem.
56
10016-10032
2013
-
-
-
-
-
-
7
-
-
-
-
-
-
3
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
7
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
736613
Wang
Tumor-targeting with novel non ...
Homo sapiens
J. Med. Chem.
56
8684-8695
2013
-
-
-
-
-
-
9
-
-
-
-
-
-
3
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
9
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
718507
Zhai
Expression, crystallization an ...
Streptococcus mutans
Acta Crystallogr. Sect. F
67
287-290
2011
-
-
1
1
-
-
-
-
-
-
-
-
-
3
-
-
1
-
-
-
-
-
-
-
1
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-
-
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-
1
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1
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1
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-
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-
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-
-
-
-
-
701528
Liang
Protein preparation, crystalli ...
Bacillus subtilis
Acta Crystallogr. Sect. F
65
709-711
2009
-
-
1
1
-
-
-
-
-
-
2
-
-
4
-
-
1
-
-
-
-
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1
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1
-
1
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2
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1
-
-
-
-
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1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
702155
McGuire
Metabolism-blocked antifolates ...
Homo sapiens
Biochem. Pharmacol.
77
1161-1172
2009
-
-
-
-
-
-
9
-
-
-
-
-
-
1
-
-
1
-
-
1
-
-
1
-
3
1
-
-
-
-
-
-
-
-
-
7
-
-
-
-
-
-
-
7
9
-
-
-
-
-
-
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-
-
1
-
1
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
705032
Deng
Synthesis and biological activ ...
Homo sapiens, Mus musculus
J. Med. Chem.
52
2940-2951
2009
-
-
1
-
-
-
8
-
-
-
-
-
-
4
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
1
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-
4
8
-
-
-
-
-
-
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-
-
-
-
2
-
-
-
-
-
-
-
-
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-
-
-
-
-
705147
Zhang
Structures of glycinamide ribo ...
Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
J. Mol. Biol.
389
722-733
2009
-
-
1
1
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-
-
-
-
-
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-
5
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
688289
Deng
Synthesis and discovery of hig ...
Homo sapiens, Mus musculus
J. Med. Chem.
51
5052-5063
2008
-
-
-
-
-
-
14
-
-
-
-
-
-
4
-
-
-
-
-
1
-
-
2
-
4
2
-
-
-
1
-
-
2
-
-
14
-
-
-
2
-
-
-
14
14
-
-
-
-
-
-
-
-
-
-
-
1
-
-
2
-
2
-
-
-
1
-
-
-
-
-
-
-
-
-
688291
DeMartino
Asymmetric synthesis of inhibi ...
Homo sapiens
J. Med. Chem.
51
5441-5448
2008
-
1
1
-
-
-
16
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
3
-
-
-
-
-
-
-
1
13
-
40
-
1
1
1
-
-
-
40
16
13
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
685128
Manieri
Human glycinamide ribonucleoti ...
Homo sapiens
Biochemistry
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672527
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Synthesis and biological evalu ...
Escherichia coli, Homo sapiens
Bioorg. Med. Chem.
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Cheng
Synthesis and biological evalu ...
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Bioorg. Med. Chem.
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2
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673825
Woehlke
Molecular characterization and ...
Bos taurus
Gene
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2005
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30
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658000
Zhang
Rational design, synthesis, ev ...
Homo sapiens
Biochemistry
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1
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3
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660458
Lee
On the structural and function ...
Homo sapiens
Protein Sci.
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1
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1
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10
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1
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12
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10
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1
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12
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485736
McMorran
Involvement of a transformylas ...
Arabidopsis thaliana, Bacillus subtilis, Drosophila melanogaster, Escherichia coli, Pseudomonas aeruginosa, Saccharomyces cerevisiae
Microbiology
147
1517-1524
2001
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1
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1
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1
2
5
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9
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12
1
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1
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5
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12
1
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485740
Gooljarsingh
Localization of GAR transformy ...
Escherichia coli, Homo sapiens
Proc. Natl. Acad. Sci. USA
98
6565-6570
2001
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2
2
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2
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1
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4
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2
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1
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4
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485730
Liu
The unexpected catalytic prope ...
Escherichia coli
Bioorg. Chem.
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2000
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1
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6
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2
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1
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6
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1
1
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1
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485733
Nixon
Improvement in the efficiency ...
Escherichia coli
Protein Eng.
13
323-327
2000
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1
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4
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1
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1
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1
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485735
Antle
Substrate specificity of human ...
Escherichia coli, Gallus gallus, Homo sapiens
Arch. Biochem. Biophys.
370
231-235
1999
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2
1
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5
4
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4
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1
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1
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14
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2
1
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5
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4
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3
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1
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1
-
-
14
-
-
-
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485741
Shim
Evaluation of the kinetic mech ...
Escherichia coli
Biochemistry
38
10024-10031
1999
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1
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1
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7
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1
1
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2
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1
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2
2
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1
1
1
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1
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1
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7
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1
1
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1
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2
2
-
-
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1
1
1
-
-
-
-
-
-
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485739
Shim
Evaluation of the kinetic mech ...
Escherichia coli, Homo sapiens, Mus musculus
Biochemistry
37
8776-8782
1998
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-
1
-
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4
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3
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4
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1
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9
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1
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4
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3
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1
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-
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9
-
-
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-
-
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485731
Sanghani
Tight binding of folate substr ...
Escherichia coli, Gallus gallus, Homo sapiens, Mus musculus
Biochemistry
36
10506-10516
1997
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3
1
1
-
-
14
2
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-
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5
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6
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1
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1
1
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16
-
4
-
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3
1
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1
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-
14
-
2
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5
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1
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1
1
-
16
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
485734
Caperelli
The human glycinamide ribonucl ...
Bacillus subtilis, Escherichia coli, Gallus gallus, Homo sapiens, Saccharomyces cerevisiae
Arch. Biochem. Biophys.
341
98-103
1997
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2
1
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2
2
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3
5
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8
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1
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1
-
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14
5
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-
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2
1
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-
-
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2
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2
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3
5
-
-
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1
-
1
-
-
14
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
658380
Shi
LY231514, a pyrrolo[2,3-d]pyri ...
Homo sapiens
Cancer Res.
57
1116-1123
1997
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-
-
-
-
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3
-
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2
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1
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2
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3
2
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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485729
Warren
A rapid screen of active site ...
Bacillus subtilis, Drosophila melanogaster, Escherichia coli, Gallus gallus, Homo sapiens, Saccharomyces cerevisiae
Biochemistry
35
8855-8862
1996
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1
1
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9
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1
6
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6
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1
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12
5
1
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-
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-
-
-
-
4
-
-
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1
4
1
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-
-
-
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9
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1
6
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-
1
-
-
-
-
12
5
-
-
-
-
-
-
-
-
-
-
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-
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485738
Antle
Substrate specificity of glyci ...
Escherichia coli, Gallus gallus
J. Biol. Chem.
271
6045-6049
1996
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1
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1
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2
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3
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2
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8
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1
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1
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2
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2
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2
-
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8
-
-
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-
-
-
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-
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485732
Marolewski
Cloning and characterization o ...
Escherichia coli, Escherichia coli TX635
Biochemistry
33
2531-2537
1994
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-
1
-
-
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5
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1
3
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2
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1
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2
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10
1
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-
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-
1
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-
-
-
-
-
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-
1
-
-
-
-
-
-
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5
-
1
3
-
-
-
-
1
-
-
2
-
10
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
485737
Habeck
A novel class of monoglutamate ...
Homo sapiens, Mus musculus
Cancer Res.
54
1021-1026
1994
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2
1
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-
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17
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2
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1
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5
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4
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-
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-
-
-
-
-
-
-
-
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2
1
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-
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17
-
-
-
-
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2
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-
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1
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5
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-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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1413
Caperelli
Carbocyclic substrates for de ...
Homo sapiens, Mus musculus
J. Biol. Chem.
267
9783-9787
1992
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-
-
-
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-
-
-
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2
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2
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-
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-
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6
-
-
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-
-
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-
-
-
-
-
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-
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2
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-
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
485715
Chen
Crystal structure of glycinami ...
Bacillus subtilis, Drosophila melanogaster, Escherichia coli, Homo sapiens, Mus musculus, Saccharomyces cerevisiae
J. Mol. Biol.
227
283-292
1992
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3
3
1
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5
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1
8
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10
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-
-
-
-
-
-
18
2
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-
-
-
-
-
-
-
-
-
-
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-
3
3
-
1
-
-
-
5
-
-
-
-
1
8
-
-
-
-
-
-
-
-
18
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
485719
Almassy
Structures of apo and complexe ...
Escherichia coli, Mus musculus
Proc. Natl. Acad. Sci. USA
89
6114-6118
1992
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2
1
1
-
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3
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2
2
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3
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1
-
-
-
-
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6
-
1
-
-
-
-
-
-
-
-
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-
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2
1
-
1
-
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-
3
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-
-
2
2
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-
-
1
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
485718
Inglese
Subcloning, characterization, ...
Bacillus subtilis, Cricetulus griseus, Drosophila melanogaster, Escherichia coli, Gallus gallus, Homo sapiens, Mus musculus, Saccharomyces cerevisiae
Biochemistry
29
1436-1443
1990
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1
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5
12
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8
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9
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1
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4
1
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32
6
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8
1
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2
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-
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1
2
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5
-
12
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-
4
8
-
-
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1
-
4
1
-
32
6
-
-
-
8
1
-
-
-
-
-
-
-
-
-
485720
Stura
Preliminary crystallographic i ...
Escherichia coli
J. Biol. Chem.
264
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1989
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1
1
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1
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1
1
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1
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-
1
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
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-
-
1
-
-
-
-
1
1
-
-
-
1
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
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-
-
-
-
485725
Caperelli
Mammalian glycinamide ribonucl ...
Drosophila melanogaster, Gallus gallus, Homo sapiens, Mus musculus
J. Biol. Chem.
264
5053-5057
1989
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2
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6
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3
4
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5
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1
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2
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11
-
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-
-
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-
-
-
-
-
-
-
2
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-
-
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-
-
6
-
-
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-
3
4
-
-
-
1
-
2
-
-
11
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
485717
Caperelli
Carbocyclic glycinamide ribonu ...
Mus musculus
Arch. Biochem. Biophys.
264
340-342
1988
-
-
-
-
-
-
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2
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2
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1
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1
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1
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4
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-
-
1
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-
-
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1
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-
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2
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-
-
2
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1
-
1
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
485711
Hards
-
Purification of mammalian glyc ...
Rattus norvegicus
Adv. Exp. Med. Biol.
195
315-319
1986
-
-
-
-
-
-
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1
1
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1
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1
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1
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3
1
1
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-
-
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-
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1
1
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1
-
1
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3
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1312
Daubner
A multifunctional protein poss ...
Drosophila melanogaster, Gallus gallus, Saccharomyces cerevisiae, Schizosaccharomyces pombe
Biochemistry
24
7059-7062
1985
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1
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4
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5
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1
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2
1
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9
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-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
4
-
-
-
1
-
2
1
-
9
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
485724
Caperelli
Mammalian glycinamide ribonucl ...
Gallus gallus, Mus musculus
Biochemistry
24
1316-1320
1985
-
1
-
-
-
-
-
4
-
-
4
4
-
3
-
-
1
-
-
3
1
-
7
3
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
1
-
-
-
-
-
-
4
-
-
4
4
-
-
-
1
-
3
1
-
7
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
485721
Young
An antibody probe to determine ...
Gallus gallus, Mus musculus
Biochemistry
23
3979-3986
1984
-
-
-
-
-
-
-
-
-
-
4
2
-
3
-
-
1
-
-
3
1
-
6
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4
2
-
-
-
1
-
3
1
-
6
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
485714
Smith
L(-)-10-formyltetrahydrofolate ...
Escherichia coli, Gallus gallus
Biochemistry
20
4034-4036
1981
-
-
-
-
-
-
1
3
-
-
-
1
-
3
-
-
-
-
-
2
-
-
3
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
3
-
-
-
-
1
-
3
-
-
-
1
-
-
-
-
-
2
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
172166
Caperelli
Purification of a complex cata ...
Columba sp., Gallus gallus, Oryctolagus cuniculus, Ovis aries, Saccharomyces cerevisiae, Sus scrofa
J. Biol. Chem.
255
1885-1890
1980
-
-
-
-
-
-
-
-
-
-
8
5
-
6
-
-
6
-
-
5
1
-
12
3
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
8
5
-
-
-
6
-
5
1
-
12
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
485728
Smith
Characterization of the enzyme ...
Escherichia coli, Gallus gallus
Biochemistry
19
4313-4321
1980
-
-
-
-
-
-
-
-
-
-
1
2
-
2
-
-
1
-
-
-
-
-
5
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
2
-
-
-
1
-
-
-
-
5
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
485712
Caperelli
-
Purification of glycineamide r ...
Gallus gallus
Dev. Biochem.
4
371-376
1979
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
1
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
485716
Caperelli
Purification of glycineamide r ...
Gallus gallus, Ovis aries, Saccharomyces cerevisiae, Sus scrofa
Biochem. Biophys. Res. Commun.
82
403-410
1978
1
-
-
-
-
-
-
-
-
1
7
4
-
4
-
-
1
-
-
3
1
-
11
6
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
1
7
4
-
-
-
1
-
3
1
-
11
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
485727
Dev
N10-Formyltetrahydrofolate is ...
Escherichia coli, Escherichia coli B / ATCC 11303, Gallus gallus, Salmonella enterica subsp. enterica serovar Typhimurium
J. Biol. Chem.
253
4242-4244
1978
-
-
-
-
-
-
-
1
-
-
-
2
-
179
-
-
2
-
-
1
-
-
8
-
1
-
-
-
-
-
-
-
3
-
-
-
-
-
-
3
-
-
-
-
-
-
1
-
-
-
2
-
-
-
2
-
1
-
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
485742
Hartman
Biosynthesis of the purines. X ...
Gallus gallus
J. Biol. Chem.
234
1812-1816
1959
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
1
-
-
1
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
1
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
485713
Warren
Biosynthesis of the purines. X ...
Clostridium cylindrosporum, Columba sp., Gallus gallus
J. Biol. Chem.
229
613-626
1957
3
-
-
-
-
-
1
2
-
-
-
3
-
3
-
-
1
-
-
2
1
1
10
-
1
-
-
-
-
1
-
-
-
-
-
-
3
-
-
-
-
-
-
-
1
-
2
-
-
-
3
-
-
-
1
-
2
1
1
10
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-