Activating Compound | Comment | Organism | Structure |
---|---|---|---|
NH4+ | activity enhanced by | Gallus gallus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
K+ | activity enhanced by | Gallus gallus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
63000 | - |
2 * 63000, transformylase, homodimer, SDS-PAGE | Gallus gallus |
83000 | - |
2 * 83000, trifunctional protein, SDS-PAGE | Gallus gallus |
100000 | - |
protein possessing transformylase activity, sucrose density gradient ultracentrifugation | Gallus gallus |
150000 | - |
gel filtration | Saccharomyces cerevisiae |
160000 | - |
trifunctional protein, sucrose density gradient ultracentrifugation | Gallus gallus |
201000 | - |
gel filtration | Ovis aries |
218000 | - |
gel filtration | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide | Gallus gallus | - |
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide | - |
? | |
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide | Sus scrofa | - |
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide | - |
? | |
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide | Saccharomyces cerevisiae | - |
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide | - |
? | |
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide | Ovis aries | - |
tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gallus gallus | - |
chicken | - |
Ovis aries | - |
sheep | - |
Saccharomyces cerevisiae | - |
yeast | - |
Sus scrofa | - |
pig | - |
Purification (Comment) | Organism |
---|---|
purified in combination with formyl-methenyl-methylenetetrahydrofolate synthetase | Gallus gallus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Gallus gallus | - |
liver | - |
Sus scrofa | - |
liver | - |
Ovis aries | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
1.294 | - |
- |
Gallus gallus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide | - |
Gallus gallus | tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide | - |
? | |
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide | - |
Sus scrofa | tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide | - |
? | |
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide | - |
Saccharomyces cerevisiae | tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide | - |
? | |
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide | - |
Ovis aries | tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide | - |
? | |
additional information | 3 activities in a multifunctional protein, posessing glycinamide ribonucleotide synthetase, glycinamide ribonucleotidetransformylase and aminoimidazole ribonucleotide synthetase | Gallus gallus | ? | - |
? | |
additional information | 3 activities in a multifunctional protein, posessing glycinamide ribonucleotide synthetase, glycinamide ribonucleotidetransformylase and aminoimidazole ribonucleotide synthetase | Sus scrofa | ? | - |
? | |
additional information | 3 activities in a multifunctional protein, posessing glycinamide ribonucleotide synthetase, glycinamide ribonucleotidetransformylase and aminoimidazole ribonucleotide synthetase | Ovis aries | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | homodimer | Gallus gallus |
dimer | homodimer | Saccharomyces cerevisiae |
dimer | homodimer | Ovis aries |
dimer | 2 * 63000, transformylase, homodimer, SDS-PAGE | Gallus gallus |
dimer | 2 * 83000, trifunctional protein, SDS-PAGE | Gallus gallus |
monomer | - |
Gallus gallus |
monomer | - |
Sus scrofa |
monomer | - |
Saccharomyces cerevisiae |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
L-(+-)-5,10-methenyltetrahydrofolate | - |
Gallus gallus |