Literature summary for 2.1.2.2 extracted from

Caperelli, C.A.; Liu, D.
Carbocyclic substrates for de novo purine biosynthesis. Enantiospecific synthesis and enantiospecificity of enzymatic utilization (1992), J. Biol. Chem., 267, 9783-9787.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide	Mus musculus	essential enzyme in DNA synthesis, third enzyme in de novo purine biosynthesis pathway	tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide	-	?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide	Homo sapiens	essential enzyme in DNA synthesis, third enzyme in de novo purine biosynthesis pathway	tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	human	-
Mus musculus	-	mouse	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide	-	Mus musculus	tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide	-	?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide	-	Homo sapiens	tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide	-	?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide	essential enzyme in DNA synthesis, third enzyme in de novo purine biosynthesis pathway	Mus musculus	tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide	-	?
10-formyltetrahydrofolate + 5-phospho-D-ribosylglycinamide	essential enzyme in DNA synthesis, third enzyme in de novo purine biosynthesis pathway	Homo sapiens	tetrahydrofolate + 5'-phosphoribosyl-N-formylglycinamide	-	?
10-formyltetrahydrofolate + carbocyclic beta-glycinamide ribonucleotide	-	Mus musculus	tetrahydrofolate + formyl glycinamide ribonucleotide	-	?
10-formyltetrahydrofolate + carbocyclic beta-glycinamide ribonucleotide	-	Homo sapiens	tetrahydrofolate + formyl glycinamide ribonucleotide	-	?

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Release 2023.1 (January 2023)