Application | Comment | Organism |
---|---|---|
medicine | enzyme is a target for antibiotics | Escherichia coli |
medicine | the cytosolic SHMT is a target enzyme for chemotherapy | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the enzyme plays an indispensable role in nucleic acid biosynthesis | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Ser + tetrahydrofolate | - |
Escherichia coli | Gly + 5,10-methylenetetrahydrofolate | - |
r | |
L-Ser + tetrahydrofolate | - |
Homo sapiens | Gly + 5,10-methylenetetrahydrofolate | - |
r | |
additional information | the enzyme plays an indispensable role in nucleic acid biosynthesis | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
eSHMT | - |
Escherichia coli |
hSHMT | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Escherichia coli | |
pyridoxal 5'-phosphate | - |
Homo sapiens |