Literature summary for 2.1.1.99 extracted from

De Luca, V.; Balsevich, J.; Tyler, R.T.; Eilert, U.; Panchuk, B.D.; Kurz, W.G.W.
Biosynthesis of indole alkaloids: developmental regulation of the biosynthethic pathway from tabersonine to vindoline in Catheranthus roseus (1986), J. Plant Physiol., 125, 147-156.

No PubMed abstract available

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
S-adenosyl-L-methionine + 16-methoxy-2,3-dihydro-3-hydroxytabersonine	Catharanthus roseus	enzyme is involved in the biosynthesis of vindoline from tabersonine	S-adenosyl-L-homocysteine + deacetoxyvindoline	-	?

Organism

Organism	UniProt	Comment	Textmining
Catharanthus roseus	-	-	-

Reaction

Reaction	Comment	Organism	Reaction ID
S-adenosyl-L-methionine + 3-hydroxy-16-methoxy-2,3-dihydrotabersonine = S-adenosyl-L-homocysteine + deacetoxyvindoline	summerization of biosynthetic pathway of vindoline	Catharanthus roseus	a

Source Tissue

Source Tissue	Comment	Organism	Textmining
seed	-	Catharanthus roseus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + 16-methoxy-2,3-dihydro-3-hydroxytabersonine	-	Catharanthus roseus	S-adenosyl-L-homocysteine + deacetoxyvindoline	i.e. N(1)-methyl-16-methoxy-2,3-dihydro-3-hydroxytabersonine	?
S-adenosyl-L-methionine + 16-methoxy-2,3-dihydro-3-hydroxytabersonine	enzyme is involved in the biosynthesis of vindoline from tabersonine	Catharanthus roseus	S-adenosyl-L-homocysteine + deacetoxyvindoline	-	?

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Release 2023.1 (January 2023)