General Stability | Organism |
---|---|
freezing destroys activity | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
S-adenosyl-L-homocysteine | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Rattus norvegicus | |
0.00054 | - |
4-Chlorothiophenol | - |
Rattus norvegicus | |
0.0011 | - |
phenyl sulfide | - |
Rattus norvegicus | |
0.0028 | - |
4-Nitrothiophenol | - |
Rattus norvegicus | |
0.012 | - |
Diethylthiocarbamoyl sulfide | - |
Rattus norvegicus | |
0.043 | - |
2-Thioacetanilide | - |
Rattus norvegicus | |
0.11 | - |
2-Benzimidazole thiol | - |
Rattus norvegicus | |
0.19 | - |
thioglycolic acid | - |
Rattus norvegicus | |
0.21 | - |
L-cysteine methyl ester | - |
Rattus norvegicus | |
0.4 | - |
N-acetyl-L-cysteine | - |
Rattus norvegicus | |
1 | - |
6-Propyl-2-thiouracil | - |
Rattus norvegicus | |
1.2 | - |
2-mercaptopropionic acid | - |
Rattus norvegicus | |
1.4 | - |
1-methylimidazol-2-thiol | - |
Rattus norvegicus | |
1.6 | - |
2,3-Dimercaptopropanol | - |
Rattus norvegicus | |
4.7 | - |
3-mercaptopropionic acid methyl ester | - |
Rattus norvegicus | |
8.1 | - |
2-mercaptoethanol | - |
Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
27500 | - |
1 * 27500, SDS-PAGE | Rattus norvegicus |
28000 | - |
gel filtration | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
S-adenosyl-L-methionine + a thiol = S-adenosyl-L-homocysteine + a methyl thioether | mechanism | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.01 | - |
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-methylimidazole-2-thiol + S-adenosyl-L-methionine | - |
Rattus norvegicus | 1-methyl-2-(methylthio)-1H-imidazole + S-adenosyl-L-homocysteine | - |
? | |
2,3-dimercaptopropanol + S-adenosyl-L-methionine | - |
Rattus norvegicus | ? + S-adenosyl-L-homocysteine | - |
? | |
2-benzimidazole thiol + S-adenosyl-L-methionine | - |
Rattus norvegicus | ? + S-adenosyl-L-homocysteine | - |
? | |
2-mercaptobenzothiazole + S-adenosyl-L-methionine | - |
Rattus norvegicus | S-methyl-2-mercaptobenzothiazole + S-adenosyl-L-homocysteine | - |
? | |
2-mercaptoethanol + S-adenosyl-L-methionine | - |
Rattus norvegicus | S-methyl-2-mercaptoethanol + S-adenosyl-L-homocysteine | - |
? | |
2-mercaptopropionic acid + S-adenosyl-L-methionine | - |
Rattus norvegicus | S-methyl-2-mercaptopropionic acid + S-adenosyl-L-homocysteine | - |
? | |
2-thioacetanilide + S-adenosyl-L-methionine | - |
Rattus norvegicus | S-methyl-2-thioacetanilide + S-adenosyl-L-homocysteine | - |
? | |
3-mercaptopropionic acid methyl ester + S-adenosyl-L-methionine | - |
Rattus norvegicus | S-methyl-3-mercaptopropionic acid methyl ester + S-adenosyl-L-homocysteine | - |
? | |
4-chlorothiophenol + S-adenosyl-L-methionine | - |
Rattus norvegicus | 4-chloro-S-methylphenylmercaptan + S-adenosyl-L-homocysteine | - |
? | |
4-nitrothiophenol + S-adenosyl-L-methionine | - |
Rattus norvegicus | 4-nitro-S-methylphenylmercaptan + S-adenosyl-L-homocysteine | - |
? | |
6-propyl-2-thiouracil + S-adenosyl-L-methionine | - |
Rattus norvegicus | 6-propyl-S-methyl-2-thiouracil + S-adenosyl-L-homocysteine | - |
? | |
6-thiopurine + S-adenosyl-L-methionine | - |
Rattus norvegicus | S-methyl-6-thiopurine + S-adenosyl-L-homocysteine | - |
? | |
benzylmercaptan + S-adenosyl-L-methionine | - |
Rattus norvegicus | benzylmethylsulfide + S-adenosyl-L-homocysteine | - |
? | |
diethylthiocarbamoyl sulfide + S-adenosyl-L-methionine | - |
Rattus norvegicus | ? + S-adenosyl-L-homocysteine | - |
? | |
L-cysteine methyl ester + S-adenosyl-L-methionine | - |
Rattus norvegicus | S-methyl-L-cysteine methyl ester + S-adenosyl-L-homocysteine | - |
? | |
mercaptoacetic acid + S-adenosyl-L-methionine | - |
Rattus norvegicus | S-methylmercaptoacetic acid + S-adenosyl-L-homocysteine | - |
? | |
N-acetyl-L-cysteine + S-adenosyl-L-methionine | - |
Rattus norvegicus | N-acetyl-S-methyl-L-cysteine + S-adenosyl-L-homocysteine | - |
? | |
phenyl sulfide + S-adenosyl-L-methionine | - |
Rattus norvegicus | ? + S-adenosyl-L-homocysteine | - |
? | |
thiophenol + S-adenosyl-L-methionine | - |
Rattus norvegicus | S-methylphenylmercaptan + S-adenosyl-L-homocysteine | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 27500, SDS-PAGE | Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
- |
Rattus norvegicus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6.6 | 8.6 | about 50% of maximum activity at pH 6.6 and pH 8.6 | Rattus norvegicus |