Literature summary for 2.1.1.86 extracted from

Upadhyay, V.; Ceh, K.; Tumulka, F.; Abele, R.; Hoffmann, J.; Langer, J.; Shima, S.; Ermler, U.
Molecular characterization of methanogenic N5-methyl-tetrahydromethanopterin coenzyme M methyltransferase (2016), Biochim. Biophys. Acta, 1858, 2140-2144 .

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasmic membrane	-	Methanothermobacter marburgensis	-	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
430000	-	laser induced liquid bead ion desorption mass spectrometry or gel filtration and multi-angle light scattering	Methanothermobacter marburgensis

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
5-methyl-5,6,7,8-tetrahydromethanopterin + CoM + 2 Na+/in	Methanothermobacter marburgensis	-	5,6,7,8-tetrahydromethanopterin + 2-(methylsulfanyl)ethane-1-sulfonate + 2 Na+/out	-	ir

Organism

Organism	UniProt	Comment	Textmining
Methanothermobacter marburgensis	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
DEAE Sepharose column chromatography and Superose-6 gel filtration	Methanothermobacter marburgensis

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5-methyl-5,6,7,8-tetrahydromethanopterin + CoM + 2 Na+/in	-	Methanothermobacter marburgensis	5,6,7,8-tetrahydromethanopterin + 2-(methylsulfanyl)ethane-1-sulfonate + 2 Na+/out	-	ir

Subunits

Subunits	Comment	Organism
heterotrimer	-	Methanothermobacter marburgensis

Synonyms

Synonyms	Comment	Organism
MTR	-	Methanothermobacter marburgensis
MtrABCDEFGH	-	Methanothermobacter marburgensis
N5-methyl-tetrahydromethanopterin: coenzyme M methyltransferase	-	Methanothermobacter marburgensis

Cofactor

Cofactor	Comment	Organism	Structure
Cobalamin	-	Methanothermobacter marburgensis

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Release 2023.1 (January 2023)