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Literature summary for 2.1.1.8 extracted from

  • Dave, S.; Rahatgaonkar, A.
    Computational evaluation of 2-phenyl-4H-chromen-4-one analogues as antihistamines: Potential histamine N-methyltransferase (HMT) inhibitors (2009), E-J. Chem., 6, 1009-1016.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
2-(4-hydroperoxyphenyl)-6-methyl-4H-chromen-4-one
-
Homo sapiens
3,6-dimethyl-2-phenyl-4H-chromen-4-one
-
Homo sapiens
3-bromo-6-chloro-2-phenyl-4H-chromen-4-one
-
Homo sapiens
3-bromo-6-methyl-2-phenyl-4H-chromen-4-one
-
Homo sapiens
3-chloro-6-methyl-2-phenyl-4H-chromen-4-one
-
Homo sapiens
6-chloro-2-phenyl-4H-chromen-4-one
-
Homo sapiens
6-methyl-2-phenyl-4H-chromen-4-one
-
Homo sapiens
8-bromo-6-chloro-2-phenyl-4H-chromen-4-one
-
Homo sapiens
8-bromo-6-methyl-2-phenyl-4H-chromen-4-one
-
Homo sapiens
N-[2(benzhydryloxy)ethyl] N N-dimethylamine diphenhydramine, competitive inhibitor Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + histamine
-
Homo sapiens S-adenosyl-L-homocysteine + Ntau-methylhistamine
-
?

Synonyms

Synonyms Comment Organism
HMT
-
Homo sapiens