Literature summary for 2.1.1.79 extracted from

Palacios-Chaves, L.; Zuniga-Ripa, A.; Gutierrez, A.; Gil-Ramirez, Y.; Conde-Alvarez, R.; Moriyon, I.; Iriarte, M.
Identification and functional analysis of the cyclopropane fatty acid synthase of Brucella abortus (2012), Microbiology, 158, 1037-1044.

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Organism

Organism	UniProt	Comment	Textmining
Brucella abortus	-	-	-
Brucella abortus 2308 NalR	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + phospholipid olefinic fatty acid	-	Brucella abortus	S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid	-	?
S-adenosyl-L-methionine + phospholipid olefinic fatty acid	-	Brucella abortus 2308 NalR	S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid	-	?

Synonyms

Synonyms	Comment	Organism
CFA synthase	-	Brucella abortus
cyclopropane fatty acid synthase	-	Brucella abortus

Expression

Organism	Comment	Expression
Brucella abortus	enzyme expression is promoted by acid pH and high osmolarity	up

General Information

General Information	Comment	Organism
malfunction	enzyme deficiency does not alter the ability of Brucella abortus to multiply in RAW 264.7 macrophages and in mice	Brucella abortus
physiological function	the enzyme is useful for survival extracellularly, thus facilitating persistence in contaminated materials and transmission to new hosts	Brucella abortus

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Release 2023.1 (January 2023)