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Literature summary for 2.1.1.77 extracted from

  • Ingrosso, D.; Kagan, R.M.; Clarke, S.
    Distinct C-terminal sequences of isozymes I and II of the human erythrocyte L-isoaspartyl/D-aspartyl protein methyltransferase [published erratum appears in Biochem Biophys Res Commun 1991 Apr 15;176(1):549] (1991), Biochem. Biophys. Res. Commun., 175, 351-358.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
sequence analysis of a cDNA clone of a rat brain enzyme Rattus norvegicus
southern blot analysis of PCR amplified genomic DNA, human chromosome contains a single gene encoding the enzyme, PCMT1, mapped to the q24-25 region of chromosome 6 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
24630
-
amino acid sequence Rattus norvegicus
25000
-
-
Homo sapiens
25000
-
-
Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + protein L-isoaspartate Salmonella enterica subsp. enterica serovar Typhimurium
-
S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
S-adenosyl-L-methionine + protein L-isoaspartate Drosophila melanogaster
-
S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
S-adenosyl-L-methionine + protein L-isoaspartate Mus musculus
-
S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
S-adenosyl-L-methionine + protein L-isoaspartate Escherichia coli
-
S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
S-adenosyl-L-methionine + protein L-isoaspartate Homo sapiens
-
S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
S-adenosyl-L-methionine + protein L-isoaspartate Rattus norvegicus
-
S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
S-adenosyl-L-methionine + protein L-isoaspartate Bos taurus
-
S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
S-adenosyl-L-methionine + protein L-isoaspartate Oryctolagus cuniculus
-
S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
bovine
-
Drosophila melanogaster
-
-
-
Escherichia coli
-
-
-
Homo sapiens
-
human
-
Mus musculus
-
-
-
Oryctolagus cuniculus
-
rabbit
-
Rattus norvegicus
-
-
-
Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Mus musculus
-
brain
-
Homo sapiens
-
brain
-
Rattus norvegicus
-
brain
-
Bos taurus
-
brain
-
Oryctolagus cuniculus
-
erythrocyte
-
Mus musculus
-
erythrocyte
-
Homo sapiens
-
erythrocyte
-
Rattus norvegicus
-
erythrocyte
-
Bos taurus
-
heart
-
Mus musculus
-
heart
-
Oryctolagus cuniculus
-
liver
-
Mus musculus
-
liver
-
Rattus norvegicus
-
liver
-
Oryctolagus cuniculus
-
muscle
-
Oryctolagus cuniculus
-
placenta
-
Homo sapiens
-
testis
-
Mus musculus
-
testis
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + protein D-aspartate
-
Escherichia coli S-adenosyl-L-homocysteine + protein D-aspartate beta-methyl ester
-
?
S-adenosyl-L-methionine + protein D-aspartate
-
Homo sapiens S-adenosyl-L-homocysteine + protein D-aspartate beta-methyl ester
-
?
S-adenosyl-L-methionine + protein D-aspartate
-
Bos taurus S-adenosyl-L-homocysteine + protein D-aspartate beta-methyl ester
-
?
S-adenosyl-L-methionine + protein L-isoaspartate
-
Salmonella enterica subsp. enterica serovar Typhimurium S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
S-adenosyl-L-methionine + protein L-isoaspartate
-
Drosophila melanogaster S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
S-adenosyl-L-methionine + protein L-isoaspartate
-
Mus musculus S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
S-adenosyl-L-methionine + protein L-isoaspartate
-
Escherichia coli S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
S-adenosyl-L-methionine + protein L-isoaspartate
-
Homo sapiens S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
S-adenosyl-L-methionine + protein L-isoaspartate
-
Rattus norvegicus S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
S-adenosyl-L-methionine + protein L-isoaspartate
-
Bos taurus S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?
S-adenosyl-L-methionine + protein L-isoaspartate
-
Oryctolagus cuniculus S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
?

Subunits

Subunits Comment Organism
monomer
-
Escherichia coli
monomer
-
Bos taurus
monomer 1 + 25000 Homo sapiens

Synonyms

Synonyms Comment Organism
protein carboxyl methyltransferase type II
-
Homo sapiens