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Literature summary for 2.1.1.72 extracted from

  • Lopez-Garrido, J.; Casadesus, J.
    Regulation of Salmonella enterica pathogenicity island 1 (SPI-1) by DNA adenine methylation (2009), Genetics, 184, 637-649.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.72

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Salmonella enterica Dam-dependent regulation of secretion of pathogenicity island 1 is transmitted via transcriptional regulator HilD ?
-
 ?
S-adenosyl-L-methionine + DNA adenine Salmonella enterica
-
 S-adenosyl-L-homocysteine + DNA 6-methyladenine
-
 ?

Organism

Organism UniProt Comment Textmining
Salmonella enterica
-
 serovar typhimurium
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information Dam-dependent regulation of secretion of pathogenicity island 1 is transmitted via transcriptional regulator HilD Salmonella enterica ?
-
 ?
S-adenosyl-L-methionine + DNA adenine
-
 Salmonella enterica S-adenosyl-L-homocysteine + DNA 6-methyladenine
-
 ?

Synonyms

Synonyms Comment Organism
Dam
-
 Salmonella enterica
DNA adenine methyltransferase
-
 Salmonella enterica

General Information

General Information Comment Organism
malfunction Dam negative mutants contain lowered levels of the secretion of pathogenicity island 1 transcriptional regulators HilA, HilC, HilD, and InvF. Dam negative mutants with the intestinal epithelium have been tentatively correlated with reduced secretion of pathogenicity island 1 Salmonella enterica
physiological function Dam methylation 1 may control transcription of a postranscriptional regulator of hilD expression, Dam methylation regulates the level and the stability of hilD mRNA Salmonella enterica