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Literature summary for 2.1.1.67 extracted from

  • Mei, S.; Li, X.; Gong, X.; Zhang, X.; Li, X.; Yang, L.; Zhu, L.; Zhou, H.; Liu, Y.; Zhou, A.; Zhang, X.; Zhao, Z.
    Comparison of 6-mercaptopurine with 6-thioguanine for the analysis of thiopurine S-methyltransferase activity in human erythrocyte by LC-MS/MS (2017), Biomed. Chromatogr., 31, e3959 .
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + 6-mercaptopurine
-
Homo sapiens S-adenosyl-L-homocysteine + 6-methylmercaptopurine
-
?
S-adenosyl-L-methionine + 6-thioguanine
-
Homo sapiens S-adenosyl-L-homocysteine + 6-methylthioguanine
-
?

Synonyms

Synonyms Comment Organism
thiopurine methyltransferase
-
Homo sapiens
TPMT
-
Homo sapiens