Literature summary for 2.1.1.63 extracted from

Franceschi, E.; Tosoni, A.; Minichillo, S.; Depenni, R.; Paccapelo, A.; Bartolini, S.; Michiara, M.; Pavesi, G.; Urbini, B.; Crisi, G.; Cavallo, M.A.; Tosatto, L.; Dazzi, C.; Biasini, C.; Pasini, G.; Balestrini, D.; Zanelli, F.; Ramponi, V.; Fioravanti, A.; Giombelli, E.; De Biase, D.; Baruzzi, A.
The prognostic roles of gender and O6-methylguanine-DNA methyltransferase methylation status in glioblastoma patients The female power (2018), World Neurosurg., 112, e342-e347 .

Application

Application	Comment	Organism
medicine	the enzyme methylation status is associated with longer survival in female patients compared with unmethylated females	Homo sapiens

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
DNA (containing 6-O-methylguanine) + protein L-cysteine	Homo sapiens	-	DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine	-	?

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue	Comment	Organism	Textmining
glioblastoma cell	-	Homo sapiens	-

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
DNA (containing 6-O-methylguanine) + protein L-cysteine	-	Homo sapiens	DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine	-	?

Synonyms	Comment	Organism
MGMT	-	Homo sapiens
O6-methylguanine-DNA methyltransferase	-	Homo sapiens

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Release 2023.1 (January 2023)