Protein Variants | Comment | Organism |
---|---|---|
C145A | the active site mutant shows loss of DNA repair activity | Homo sapiens |
R128A | active site mutant | Homo sapiens |
R128G | the active site mutant shows loss of DNA repair activity | Homo sapiens |
R128K | active site mutant | Homo sapiens |
Y114A | active site mutant | Homo sapiens |
Y114E | the active site mutant shows loss of DNA repair activity | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA (containing 6-O-methylguanine) + protein L-cysteine | Homo sapiens | - |
DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P16455 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA (containing 6-O-methylguanine) + protein L-cysteine | - |
Homo sapiens | DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MGMT | - |
Homo sapiens |
O6-methylguanine DNA methyltransferase | - |
Homo sapiens |