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Literature summary for 2.1.1.6 extracted from

  • Silva, R.; Ferreira, S.; Bonifacio, M.J.; Dias, J.M.; Queiroz, J.A.; Passarinha, L.A.
    Optimization of fermentation conditions for the production of human soluble catechol-O-methyltransferase by Escherichia coli using artificial neural network (2012), J. Biotechnol., 160, 161-168.
    View publication on PubMed

Application

Application Comment Organism
synthesis predictive artificial neural network models of the soluble COMT activity for production in a batch Escherichia coli culture process. Models predict a maximum COMT activity of 183.73 nmol/h, at 40°C, pH 6.5 and stirring rate of 351 rpm, and 132.90 nmol/h, at 35°C, pH 6.2 and stirring rate of 351 rpm, for semi-defined and complex medium, respectively. These results represent a 4fold increase in total activity by comparison to the standard operational conditions Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble
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Homo sapiens
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-

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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