Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ro 41-0960 | - |
Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Rattus norvegicus | - |
Sprague-Dawley rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
myometrium | levels of staining for the COMT protein in myometrium are highest on day 1 and lowest on days 8 and 13, but high levels returned by days 16 and 19 of pregnancy. Modulation of COMT activity may play a role in the regulation of myometrial contractility and cervical ripening during pregnancy | Rattus norvegicus | - |
myometrium | modulation of COMT activity may play a role in the regulation of myometrial contractility and cervical ripening during pregnancy | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-hydroxyestrogen + S-adenosyl-L-methionine | - |
Rattus norvegicus | 2-methoxyestrogen + S-adenosyl-L-homocysteine | - |
? | |
4-hydroxyestrogen + S-adenosyl-L-methionine | - |
Rattus norvegicus | 4-methoxyestrogen + S-adenosyl-L-homocysteine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
catechol-O-methyltransferase | - |
Rattus norvegicus |
COMT | - |
Rattus norvegicus |