Protein Variants | Comment | Organism |
---|---|---|
D330A | the mutation does not affect viral replication, sensitivity to mutagen, or inhibition by interferon-beta compared to the wild type | Murine hepatitis virus |
G332A | the mutant displays delayed replication kinetics and decreased peak titers relative to the wild type virus. In addition, replication of mutant virus is diminished following treatment of cells with interferon-beta, and mutant genomes are translated less efficiently both in vitro and during viral infection | Murine hepatitis virus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + a 5'-(5'-triphosphoguanosine)-[mRNA] | Murine hepatitis virus | - |
S-adenosyl-L-homocysteine + a 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Murine hepatitis virus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + a 5'-(5'-triphosphoguanosine)-[mRNA] | - |
Murine hepatitis virus | S-adenosyl-L-homocysteine + a 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] | - |
? |
Synonyms | Comment | Organism |
---|---|---|
N7-methyltransferase | - |
Murine hepatitis virus |
N7-MTase | - |
Murine hepatitis virus |
nsp14 | - |
Murine hepatitis virus |