Inhibitors | Comment | Organism | Structure |
---|---|---|---|
S-adenosyl-homocysteine | - |
Dengue virus | |
sinefungin | - |
Dengue virus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.18 | - |
S-adenosyl-L-methionine | pH 7.5, 20°C, Michaelis constants for S-adenosyl-methionine (AdoMet) in both reactions are about 10fold lower than for their respective RNA substrates, suggesting that the rate-limiting steps in methylase reactions are associated with RNA templates | Dengue virus | |
1.8 | - |
G(5')pppR-RNA | pH 7.5, 20°C, Michaelis constants for S-adenosyl-methionine (AdoMet) in both reactions are about 10fold lower than for their respective RNA substrates, suggesting that the rate-limiting steps in methylase reactions are associated with RNA templates | Dengue virus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Dengue virus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + G(5')pppR-RNA | - |
Dengue virus | S-adenosyl-L-homocysteine + m7G(5')pppR-RNA | - |
? |
Synonyms | Comment | Organism |
---|---|---|
N-7-MTase | - |
Dengue virus |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000054 | - |
S-adenosyl-L-methionine | pH 7.5, 20°C | Dengue virus | |
0.0001947 | - |
G(5')pppR-RNA | pH 7.5, 20°C | Dengue virus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00003 | - |
pH 7.5, 20°C | Dengue virus | sinefungin | |
0.00177 | - |
pH 7.5, 20°C | Dengue virus | S-adenosyl-homocysteine |